TRPM6

Transient receptor potential cation channel, subfamily M, member 6
Identifiers
Symbols TRPM6; CHAK2; HMGX; HOMG; HOMG1; HSH
External IDs OMIM: 607009 MGI: 2675603 HomoloGene: 9767 IUPHAR: TRPM6 GeneCards: TRPM6 Gene
EC number 2.7.11.1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 140803 225997
Ensembl ENSG00000119121 ENSMUSG00000024727
UniProt Q9BX84 Q8CIR4
RefSeq (mRNA) NM_001177310.1 NM_153417.1
RefSeq (protein) NP_001170781.1 NP_700466.1
Location (UCSC) Chr 9:
77.34 – 77.5 Mb		 Chr 19:
18.82 – 18.97 Mb
PubMed search [1] [2]

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.[1]

Contents

See also

References

  1. ^ Schlingmann KP, Weber S, Peters M, et al. (2002). "Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family". Nat. Genet. 31 (2): 166–70. doi:10.1038/ng889. PMID 12032568. 

Further reading

  • Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. 704. Berlin: Springer. pp. 700. ISBN 978-94-007-0264-6. 
  • Chubanov V, Gudermann T, Schlingmann KP (2006). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.". Pflugers Arch. 451 (1): 228–34. doi:10.1007/s00424-005-1470-y. PMID 16075242. 
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. 
  • Bödding M (2007). "TRPM6: A Janus-like protein.". Handb Exp Pharmacol 179 (179): 299–311. doi:10.1007/978-3-540-34891-7_18. PMID 17217065. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.