TRIP10

Thyroid hormone receptor interactor 10

PDB rendering based on 2ct4.
Identifiers
Symbols TRIP10; CIP4; HSTP; STOT; STP
External IDs OMIM604504 MGI2146901 HomoloGene99728 GeneCards: TRIP10 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 9322 106628
Ensembl ENSG00000125733 ENSMUSG00000019487
UniProt Q15642 Q8CJ53
RefSeq (mRNA) NM_004240 NM_134125
RefSeq (protein) NP_004231 NP_598886
Location (UCSC) Chr 19:
6.74 – 6.75 Mb
Chr 17:
57.39 – 57.4 Mb
PubMed search [1] [2]

Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene.[1][2][3][4]

Interactions

TRIP10 has been shown to interact with STAT3,[5] Wiskott-Aldrich syndrome protein,[6] Huntingtin,[7] CDC42,[2][6] AKAP9[8] and RHOQ.[9]

References

  1. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Jul 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974. 
  2. ^ a b Aspenstrom P (Aug 1997). "A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton". Curr Biol 7 (7): 479–87. doi:10.1016/S0960-9822(06)00219-3. PMID 9210375. 
  3. ^ Tsuji E, Tsuji Y (Apr 2001). "Molecular cloning and chromosomal localization of human salt-tolerant protein". Genetica 108 (3): 259–62. doi:10.1023/A:1004132919896. PMID 11294612. 
  4. ^ "Entrez Gene: TRIP10 thyroid hormone receptor interactor 10". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9322. 
  5. ^ Chung, Young-Hwa; Cho Nam-hyuk, Garcia Maria Ines, Lee Sun-Hwa, Feng Pinghui, Jung Jae U (Jun. 2004). "Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein". J. Virol. (United States) 78 (12): 6489–97. doi:10.1128/JVI.78.12.6489-6497.2004. ISSN 0022-538X. PMC 416526. PMID 15163742. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=416526. 
  6. ^ a b Tian, L; Nelson D L, Stewart D M (Mar. 2000). "Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules". J. Biol. Chem. (UNITED STATES) 275 (11): 7854–61. doi:10.1074/jbc.275.11.7854. ISSN 0021-9258. PMID 10713100. 
  7. ^ Holbert, Sébastien; Dedeoglu Alpaslan, Humbert Sandrine, Saudou Frédéric, Ferrante Robert J, Néri Christian (Mar. 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease". Proc. Natl. Acad. Sci. U.S.A. (United States) 100 (5): 2712–7. doi:10.1073/pnas.0437967100. ISSN 0027-8424. PMC 151406. PMID 12604778. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151406. 
  8. ^ Larocca, M Cecilia; Shanks Ryan A, Tian Lan, Nelson David L, Stewart Donn M, Goldenring James R (Jun. 2004). "AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus". Mol. Biol. Cell (United States) 15 (6): 2771–81. doi:10.1091/mbc.E03-10-0757. ISSN 1059-1524. PMC 420101. PMID 15047863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=420101. 
  9. ^ Chang, Louise; Adams Rachael D, Saltiel Alan R (Oct. 2002). "The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes". Proc. Natl. Acad. Sci. U.S.A. (United States) 99 (20): 12835–40. doi:10.1073/pnas.202495599. ISSN 0027-8424. PMC 130546. PMID 12242347. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=130546. 

Further reading