TIAF1

TGFB1-induced anti-apoptotic factor 1
Identifiers
Symbols TIAF1; MAJN; SPR210
External IDs OMIM609517 GeneCards: TIAF1 Gene
Orthologs
Species Human Mouse
Entrez 9220 n/a
Ensembl ENSG00000221995 n/a
UniProt O95411 n/a
RefSeq (mRNA) NM_004740 n/a
RefSeq (protein) NP_004731 n/a
Location (UCSC) Chr 17:
27.4 – 27.42 Mb
n/a
PubMed search [1] n/a

TGFB1-induced anti-apoptotic factor 1 is a protein that in humans is encoded by the TIAF1 gene.[1][2]

Interactions

TIAF1 has been shown to interact with Janus kinase 3[3] and TRIB3.[4]

References

  1. ^ Chang NS, Mattison J, Cao H, Pratt N, Zhao Y, Lee C (Feb 1999). "Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity". Biochem Biophys Res Commun 253 (3): 743–9. doi:10.1006/bbrc.1998.9846. PMID 9918798. 
  2. ^ "Entrez Gene: TIAF1 TGFB1-induced anti-apoptotic factor 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9220. 
  3. ^ Ji, H; Zhai Q, Zhu J, Yan M, Sun L, Liu X, Zheng Z (Apr. 2000). "A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival". Biochem. Biophys. Res. Commun. (UNITED STATES) 270 (1): 267–71. doi:10.1006/bbrc.2000.2413. ISSN 0006-291X. PMID 10733938. 
  4. ^ Zhou, Ying; Li Lu, Liu Qiongming, Xing Guichun, Kuai Xuezhang, Sun Jing, Yin Xiushan, Wang Jian, Zhang Lingqiang, He Fuchu (May. 2008). "E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3". Cell. Signal. (England) 20 (5): 942–8. doi:10.1016/j.cellsig.2008.01.010. ISSN 0898-6568. PMID 18276110. 

Further reading