Streptogramin

Streptogramins are a class of antibiotics.^[1]

Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly-growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A and streptogramin B.

Members include:

Quinupristin/dalfopristin
Pristinamycin
Virginiamycin
NXL 103, an experimental streptogramin in clinical trials for the treatment of respiratory tract infections.^[2]

References

^ University of Leeds: Antimicrobial Chemotherapy
^ Boucheer HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB, et al. Bad Bugs, no drugs: No ESKAPE! An Update from the Infectious Society of America. Clin Infect Dis. 2009;48:1-12.

-mycin (Streptomyces)	Streptomycin^# Neomycin^# (Framycetin, Paromomycin, Ribostamycin) Kanamycin^# (Amikacin, Arbekacin, Bekanamycin, Dibekacin, Tobramycin) Spectinomycin^# • Hygromycin B Paromomycin

-micin (Micromonospora)	Gentamicin^# (Netilmicin, Sisomicin, Isepamicin) Verdamicin Astromicin

Tetracyclines	Doxycycline^# •Chlortetracycline • Clomocycline • Demeclocycline • Lymecycline • Meclocycline • Metacycline • Minocycline • Oxytetracycline • Penimepicycline • Rolitetracycline • Tetracycline

Glycylcyclines	Tigecycline

Amphenicols	Chloramphenicol^# • Azidamfenicol • Thiamphenicol • Florfenicol

Pleuromutilins	Retapamulin • Tiamulin • Valnemulin

Macrolides	Erythromycin^# • Azithromycin^# • Spiramycin • Midecamycin • Oleandomycin • Roxithromycin • Josamycin • Troleandomycin • Clarithromycin • Miocamycin • Rokitamycin • Dirithromycin • Flurithromycin • Ketolide (Telithromycin, Cethromycin, Solithromycin)

Lincosamides	Clindamycin^# • Lincomycin

Streptogramins	Pristinamycin • Quinupristin/dalfopristin • Virginiamycin

Steroid antibacterials	Fusidic acid

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)