| Type | Private |
|---|---|
| Industry | Software Life Sciences |
| Founded | 2000 |
| Headquarters | Bangalore, Karnataka, India |
| Key people | Vijay Chandru, CEO Ramesh Hariharan, CTO Kas Subramanian, CSO |
| Products | Avadis Avadis NGS Sarchitect |
| Website | strandlifesciences.com |
Strand Life Sciences, formerly Strand Genomics, is a Bangalore, India-based in silico technology company. Strand focuses in data mining, predictive modeling, computational chemistry, software engineering, bioinformatics, and research biology to develop software and services for life sciences research. Strand also offers custom solutions based on its intellectual property. In August 2007, Strand and Agilent Technologies, Inc. entered an agreement in which Strand develops and supports Agilent's GeneSpring[1] software. In October 2010, Strand and Agilent renewed the agreement[2] for Strand to expand the scope of Agilent's GeneSpring across multiple life sciences disciplines.
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Strand Life Sciences was founded in October 2000 by Professors Vijay Chandru, Ramesh Hariharan, Swami Manohar, and V. Vinay. It was registered as Strand Genomics, but was later renamed to Strand Life Sciences as it dealt with various other aspects of life sciences.
Avadis is a comprehensive data mining and visualization platform. It combines the power of scalable algorithms and dynamic interactive visualization. The platform was customized for various scientific domains like gene expression, next-generation sequencing, pre-clinical research, chemistry and healthcare.
Sarchitect is a platform for modeling and predicting drug-relevant properties of molecules in silico.
ArrayAssist was developed for Stratagene, Inc., based on the Avadis platform. The production was stopped after Stratagene was acquired by Agilent Technologies, Inc. in 2007.
GeneSpring GX (version 9.0.0 onwards), GeneSpring Workgroup (version 7.0.0 onwards), and Mass Profiler Pro are developed by Strand's R&D division in Bangalore.
Avadis NGS is a software platform for next-generation sequencing data analysis. It can import pre-aligned read sequences from sequencing platforms like Illumina, ABI, and 454 Life Sciences and supports fragment, paired-end and mate-pair library types. Aligned reads in SAM, BAM, BED or Eland formats can be imported into the tool.
Avadis NGS also allows users to perform quality control on the imported data and filter reads before the main analysis is performed. Version 1.1 of the tool supports three experiment types: ChIP-Seq, RNA-Seq, and DNA-Seq. Gene, transcript, SNP, homology, gene ontology (GO), and other annotations needed for analysis can be downloaded directly from the Avadis NGS website.
Visualization tools, namely Genome Browser, Gene View, and Variant Support View, are a key aspect of the software. Other visualizations available with tool are scatter plot, MvA plot, profile plot, histogram, heat map, box and whisker plot, and Venn diagram. Aided with visualizations, users a pictorial feel for statistical trends in the data.
Avadis NGS also provides access to organism-specific interaction databases containing relations between proteins, small molecules, enzymes, complexes, biological processes, molecular functions, and gene families. The two million interactions present in these databases can also be augmented by importing pathways in BioPAX format from Reactome, Cancer Cell Map, etc. Gene lists generated by analysis steps can be used as the starting point for many pathway analysis operations.