Stillbirth

Stillbirth
Classification and external resources

Ultrasonography is often used to diagnose stillbirth.
ICD-10 P95
MedlinePlus 002304
eMedicine topic list
MeSH D050497

A stillbirth occurs when a fetus has died in the uterus. A wide variety of definitions exist.[1] The Australian definition specifies that fetal death is termed a stillbirth after 20 weeks gestation or the fetus weighs more than 400 grams (14 oz). Once the fetus has died, the mother may or may not have contractions and undergo childbirth. The term is often used in distinction to live birth or miscarriage. Most stillbirths occur in full-term pregnancies.

Contents

Human stillbirth

Causes

The causes of a large percentage of human stillbirths remain unknown, even in cases where extensive testing and autopsy have been performed. A rarely used term to describe these is sudden antenatal death syndrome or SADS, a phrase coined by Cacciatore & Collins in 2000.[2]

In cases where the cause is known, some possibilities of the cause of death are:

Sometimes a pregnancy is terminated deliberately during a late phase, for example for congenital anomaly. UK law requires these procedures to be registered as "stillbirths".[4]

Prenatal diagnosis

It is unknown how much time is needed for a fetus to die. Fetal behavior is consistent and a change in the fetus' movements or sleep-wake cycles can indicate fetal distress.[3] A decrease or cessation in sensations of fetal activity may be an indication of fetal distress or death, though it is not entirely uncommon for a healthy fetus to exhibit such changes, particularly near the end of a pregnancy when there is considerably little space in the uterus for the fetus to move about. Still, medical examination, including a nonstress test, is recommended in the event of any type of any change in the strength or frequency of fetal movement, especially a complete cease; most midwives and obstetricians recommend the use of a kick chart to assist in detecting any changes. Fetal distress or death can be confirmed or ruled out via fetoscopy/doptone, ultrasound, and/or electronic fetal monitoring. If the fetus is alive but inactive, extra attention will be given to the placenta and umbilical cord during ultrasound examination to ensure that there is no compromise of oxygen and nutrient delivery.

Constricted umbilical cord

When the umbilical cord is constricted (q.v. "accidents" above), the fetus experiences periods of hypoxia, and may respond by unusually high periods of kicking or struggling, to free the umbilical cord. These are sporadic if constriction is due to a change in the fetus' or mother's position, and may become worse or more frequent as the fetus grows. Extra attention should be given if mothers experience large increases in kicking from previous childbirths, especially when increases correspond to position changes.[5]

Prevention

As many of the causes are unknown or untreatable, prevention is difficult. Symptoms of bacterial infection, such as from a dental abscess, in pregnant women may also include unusual periods of incoherence and symptoms of shock, and should be treated by a physician immediately. High blood pressure, diabetes and drug use should be regulated with physician's advice. Umbilical cord constriction may be identified and observed by ultrasound.

Research published in the Journal of the American Medical Association in 2011 found a number of maternal factors associated with stillbirth. Among them: being age 40 or older, having diabetes, having a history of addiction to illegal drugs, being overweight or obese, and smoking cigarettes in the three months before getting pregnant. [6]

Prenatal maternal treatment

An in utero stillbirth does not usually present an immediate health risk to the woman and labour will usually begin spontaneously after two weeks, so the woman may choose to wait and birth the fetal remains vaginally. After two weeks, the woman is at risk of developing blood clotting problems, and labor induction is recommended at this point. In many cases, the woman will find the idea of carrying the dead fetus emotionally traumatizing and will elect to be induced. Caesarean birth is not recommended unless complications develop during vaginal birth.

Prevalence

Stillbirth is a relatively common, but often random, occurrence. The mean stillbirth rate in the United States is approximately 1 in 115 births, which is roughly 26,000 stillbirths each year, or on an average one every 20 minutes. In Australia,[7] England, Wales, and Northern Ireland, the rate is approximately 1 in every 200 births, in Scotland 1 in 167. (From The National Statistical Office and other sources.) Many stillbirths occur at fullterm to apparently healthy mothers, and a postmortem evaluation reveals a cause of death in only about 40% of autopsied cases.[8]

In developing countries, where medical care can be of low quality or unavailable, the stillbirth rate is much higher.

Legal definitions of stillbirth

Australia

In Australia any stillborn weighing more than 400 grams, or more than 20 weeks in gestation, must have its birth registered.[9]

Austria

In Austria a stillbirth is defined as birth of a child of at least 500g weight without vital signs, i.e. blood circulation, breath or muscle movements.

Canada

Beginning in 1959, "the definition of a stillbirth was revised to conform, in substance, to the definition of fetal death recommended by the World Health Organization." [10] The definition of "fetal death" promulgated by the World Health Organization in 1950 is as follows:

"Fetal death" means death prior to the complete expulsion or extraction from its mother of a product of human conception, irrespective of the duration of pregnancy and which is not an induced termination of pregnancy. The death is indicated by the fact that after such expulsion or extraction, the fetus does not breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord, or definite movement of voluntary muscles. Heartbeats are to be distinguished from transient cardiac contractions; respirations are to be distinguished from fleeting respiratory efforts or gasps.[11]

Germany

In Germany a stillbirth is defined as birth of a child of at least 500g weight without blood circulation or breath. Details for burial are varying in the federal states.[12]

Ireland

In Ireland, stillbirths must be registered as such. A stillbirth is legally defined as a child weighing at least 500 grammes, or having reached a gestational age of at least 24 weeks.[13]

United Kingdom

Throughout the United Kingdom, stillbirths must be registered by law. The Stillbirth Definition Act (1992) states: "any ‘child’ expelled or issued forth from its mother after the 24th week of pregnancy that did not breathe or show any other signs of life should be registered as a stillbirth."[14] In England and Wales, this must be done within 42 days and a Stillbirth Certificate is issued to the parent(s).[15] In Scotland, this must be done within 21 days.[16]

United States

In the United States, there is no standard definition of the term 'stillbirth'.[11] The Centers for Disease Control and Prevention collects statistical information on "live births, fetal deaths, and induced termination of pregnancy" from 57 reporting areas in the United States. Each reporting area has different guidelines and definitions for what is being reported; many do not use the term "stillbirth" at all. The federal guidelines suggests (at page 1) that fetal death and stillbirth can be interchangeable terms. The CDC definition of "fetal death" is based on the definition promulgated by the World Health Organization in 1950 (see section above on Canada). Researchers are learning more about the long term psychiatric sequelae of traumatic birth and believe the effects may be intergenerational [17]

The federal guidelines recommend reporting those fetal deaths whose birth weight is over 12.5 oz (350g), or those more than 20 weeks gestation. Forty-one areas use a definition very similar to the federal definition, thirteen areas use a shortened definition of fetal death, and three areas have no formal definition of fetal death. Only 11 areas specifically use the term 'stillbirth', often synonymously with late fetal death, however they are split between whether stillbirths are "irrespective of the duration of pregnancy", or whether some age or weight constraint is applied. A movement in the U.S. has changed the way that stillbirths are documented through vital records. Previously, only the deaths were reported. However 27 states have enacted legislation that offers some variation of a birth certificate as an option for parents who choose to pay for one MAB Legislative Page [MAB legislative page]

See also

References

  1. ^ Nguyen RH, Wilcox AJ (December 2005). "Terms in reproductive and perinatal epidemiology: 2. Perinatal terms". J Epidemiol Community Health 59 (12): 1019–21. doi:10.1136/jech.2004.023465. PMC 1732966. PMID 16286486. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1732966. "There is probably no health outcome with a greater number of conflicting, authoritative, legally mandated definitions. The basic WHO definition of fetal death is the intrauterine death of any conceptus at any time during pregnancy. However, for practical purposes, legal definitions usually require recorded fetal deaths to attain some gestational age (16, 20, 22, 24, or 28 weeks) or birth weight (350, 400, 500, or 1000 g). In the US states, there are eight different definitions by combinations of gestational age and weight, and at least as many in Europe." 
  2. ^ Collins JH (February 2002). "Umbilical cord accidents: human studies". Semin. Perinatol. 26 (1): 79–82. doi:10.1053/sper.2002.29860. PMID 11876571. 
  3. ^ a b Collins JH (M.D.). "Silent Risk: Issues About the Human Umbilical Cord" Retrieved on 2009-3-17
  4. ^ Bythell M, et al. (2008) The contribution of late termination of pregnancy to stillbirth rates in Northern England, 1994-2005. The British Journal of Obstetrics and Gynaecology, 115(5):664-666
  5. ^ http://www.preginst.com/pucp.html
  6. ^ http://www.cbsnews.com/8301-500368_162-57342588/studies-identify-stillbirth-risk-factors-causes/
  7. ^ Gordon, Adrienne (Dr). "Department of Neonatal Medicine Protocol Book: Royal Prince Alfred Hospital". http://www.sswahs.nsw.gov.au/RPA/neonatal/html/Newprot/stillbirths.html. Retrieved 2006-09-13. 
  8. ^ Cacciatore, J. (2007). A phenomenological exploration of stillbirth and the effects of ritualization on maternal anxiety and depression, University of Nebraska-Lincoln Press, Digital Commons ; Froen, J.F. (2005).
  9. ^ Lahra MM, Gordon A, Jeffery HE (2007). "Chorioamnionitis and fetal response in stillbirth". Am. J. Obstet. Gynecol. 196 (3): 229.e1–4. doi:10.1016/j.ajog.2006.10.900. PMID 17346531. "Stillbirth is defined within Australia as fetal death (no signs of life), whether antepartum or intrapartum, at ≥20 weeks of gestation or ≥400 g birthweight, if gestational age is unknown." 
  10. ^ Statistics Canada ("Canada's National Statistical Agency"), History, Vital Statistics - Stillbirth Database, in Vital Statistics – Stillbirth Database.
  11. ^ a b Centers for Disease Control and Prevention (PDF). State Definitions and Reporting Requirements (1997 Revision ed.). National Center for Health Statistics. http://www.cdc.gov/nchs/data/misc/itop97.pdf. 
  12. ^ http://www.initiative-regenbogen.de/gesetze.htm
  13. ^ http://www.citizensinformation.ie/categories/birth-family-relationships/miscarriage-and-stillbirth/registering_stillbirth
  14. ^ "Registration of Stillbirths and Certification for Pregnancy Loss before 24 Weeks Gestation" Royal College of Midwives. Retrieved September 27, 2007
  15. ^ Guide to registering stillbirths in the UK
  16. ^ Registering a stillbirth General Register Office for Scotland
  17. ^ Cacciatore, J. (2010). Unique stories of women and their families after the death of a baby. Journal of Healthcare Social Work, 49(2), 134-148.

External links