Sonodynamic therapy is an experimental cancer therapy which uses ultrasound to enhance the cytotoxic effects of drugs known as sonosensitizers. It has been tested in vitro and in animals.
Sonodynamic Therapy (SDT) also referred to as Ultrasound Activated Therapy, the synergistic effect of drugs and ultrasound, is a promising new cancer treatment. This treatment modality involves a novel sonosensitizing agent that is derived from chlorophyll, is sensitive to red light, and is extremely sensitive to ultrasound. SonneMed, LLC, a small molecule cancer therapeutics venture holds the intellectual property rights to this sonosensitizing agent. The agent is specifically absorbed in tumor cells and produces cytotoxic effects upon interaction with diagnostic-strength ultrasound. [1] The mechanism of toxicity involves at least the generation of singlet oxygen, which is cytotoxic.