Somatomedin

Somatomedin is a group of hormones that is produced, when stimulated by somatotropin (STH), to promote cell growth and division ^[1]. In this way, they mediate the effect of somatotropin (also known as growth hormone ^[2]).

They have similar biological effects to somatotropin.

Three forms include:

somatomedin A, which is another name for insulin-like growth factor 2
somatomedin B, which is derived from vitronectin^[3]
somatomedin C, which is another name for insulin-like growth factor 1

References

^ Somatomedin at eMedicine Dictionary
^ growth+hormone at eMedicine Dictionary
^ Zhou A (2007). "Functional structure of the somatomedin B domain of vitronectin". Protein Science 16 (7): 1502. doi:10.1110/ps.072819107. PMC 2206693. PMID 17567740. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2206693.

External links

MeSH Somatomedins

Intercellular signaling peptides and proteins / ligands

Growth factors	Endothelial growth factor • Epidermal growth factor • Fibroblast growth factor • Nerve growth factor • Platelet-derived growth factor • Transforming growth factor beta superfamily

Ephrin	EFNA1 • EFNA2 • EFNA3 • EFNA4 • EFNA5 • EFNB1 • EFNB2 • EFNB3

Other	Adipokine • Agouti signaling protein • Agouti-related protein • Angiogenic protein • CCN intercellular signaling protein (Cysteine-rich protein 61, Connective tissue growth factor, Nephroblastoma overexpressed protein) • Cytokine • Endothelin (EDN1, EDN2, EDN3) • Hedgehog protein • Interferon • Kinin • Parathyroid hormone-related protein • Semaphorin • Somatomedin • Tolloid-like metalloproteinase • Tumor necrosis factor • Wnt protein

see also extracellular ligand disorders B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)