Sixtus was a Roman name, a corruption of the Greek name "Ξυστος," meaning "polished," and originally Latinized "Xystus." It is not to be confused with the common Roman name "Sextus," meaning "sixth," though not necessarily denoting a sixth child.
Notable people named Sixtus include five Popes of the Roman Catholic Church, the first three of whom are called "Xystus" in the most ancient records:
Other notable people named Sixtus include:
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