STK25

Serine/threonine kinase 25
Identifiers
Symbols STK25; DKFZp686J1430; SOK1; YSK1
External IDs OMIM602255 MGI1891699 HomoloGene48428 GeneCards: STK25 Gene
EC number 2.7.11.1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 10494 59041
Ensembl ENSG00000115694 ENSMUSG00000026277
UniProt O00506 Q3U6Y0
RefSeq (mRNA) NM_006374 NM_021537.3
RefSeq (protein) NP_006365 NP_067512.3
Location (UCSC) Chr 2:
242.43 – 242.45 Mb
Chr 1:
95.52 – 95.53 Mb
PubMed search [1] [2]

Serine/threonine-protein kinase 25 is an enzyme that in humans is encoded by the STK25 gene.[1][2][3][4]

Interactions

STK25 has been shown to interact with STRN,[5] PDCD10[6] and MOBKL3.[5]

References

  1. ^ Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T (Jan 1997). "Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway". EMBO J 15 (17): 4537–46. PMC 452183. PMID 8887545. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=452183. 
  2. ^ Osada S, Izawa M, Saito R, Mizuno K, Suzuki A, Hirai S, Ohno S (Jun 1997). "YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways". Oncogene 14 (17): 2047–57. doi:10.1038/sj.onc.1201043. PMID 9160885. 
  3. ^ Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA (Mar 2004). "YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta". J Cell Biol 164 (7): 1009–20. doi:10.1083/jcb.200310061. PMC 2172068. PMID 15037601. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2172068. 
  4. ^ "Entrez Gene: STK25 serine/threonine kinase 25 (STE20 homolog, yeast)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10494. 
  5. ^ a b Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (January 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2621004. 
  6. ^ Rual JF, Venkatesan K, Hao T, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading