SRPK2
Serine/threonine-protein kinase SRPK2 is an enzyme that in humans is encoded by the SRPK2 gene.[1][2][3]
Interactions
SRPK2 has been shown to interact with U2AF2[4][2] and ASF/SF2.[2][5][6]
References
- ^ Gui JF, Lane WS, Fu XD (Jul 1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle". Nature 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
- ^ a b c Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, Fu XD (Mar 1998). "SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells". J Cell Biol 140 (4): 737–50. doi:10.1083/jcb.140.4.737. PMC 2141757. PMID 9472028. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2141757.
- ^ "Entrez Gene: SRPK2 SFRS protein kinase 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6733.
- ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct. 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- ^ Umehara, Hiroshi; Nishii Yoichi, Morishima Masaki, Kakehi Yoshiyuki, Kioka Noriyuki, Amachi Teruo, Koizumi Jun, Hagiwara Masatoshi, Ueda Kazumitsu (Feb. 2003). "Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A". Biochem. Biophys. Res. Commun. (United States) 301 (2): 324–9. doi:10.1016/S0006-291X(02)03017-6. ISSN 0006-291X. PMID 12565863.
- ^ Koizumi, J; Okamoto Y, Onogi H, Mayeda A, Krainer A R, Hagiwara M (Apr. 1999). "The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)". J. Biol. Chem. (UNITED STATES) 274 (16): 11125–31. doi:10.1074/jbc.274.16.11125. ISSN 0021-9258. PMID 10196197.
Further reading
- Bedford MT, Chan DC, Leder P (1997). "FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.". EMBO J. 16 (9): 2376–83. doi:10.1093/emboj/16.9.2376. PMC 1169838. PMID 9171351. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1169838.
- Kuroyanagi N, Onogi H, Wakabayashi T, Hagiwara M (1998). "Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles.". Biochem. Biophys. Res. Commun. 242 (2): 357–64. doi:10.1006/bbrc.1997.7913. PMID 9446799.
- Koizumi J, Okamoto Y, Onogi H, (1999). "The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)". J. Biol. Chem. 274 (16): 11125–31. doi:10.1074/jbc.274.16.11125. PMID 10196197.
- Daub H, Blencke S, Habenberger P, (2002). "Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein". J. Virol. 76 (16): 8124–37. doi:10.1128/JVI.76.16.8124-8137.2002. PMC 155132. PMID 12134018. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=155132.
- Strausberg RL, Feingold EA, Grouse LH, (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Hillier LW, Fulton RS, Fulton LA, (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Ota T, Suzuki Y, Nishikawa T, (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brill LM, Salomon AR, Ficarro SB, (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
- Gerhard DS, Wagner L, Feingold EA, (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Rush J, Moritz A, Lee KA, (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
- Zheng Y, Fu XD, Ou JH (2005). "Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein". Virology 342 (1): 150–8. doi:10.1016/j.virol.2005.07.030. PMID 16122776.
- Rual JF, Venkatesan K, Hao T, (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Ewing RM, Chu P, Elisma F, (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.