SLC2A7

Solute carrier family 2 (facilitated glucose transporter), member 7

Rendering based on PDB 1yg7.
Identifiers
Symbols SLC2A7; GLUT7
External IDs OMIM: 610371 MGI: 3650865 HomoloGene: 72470 GeneCards: SLC2A7 Gene
Orthologs
Species Human Mouse
Entrez 155184 435818
Ensembl ENSG00000197241 ENSMUSG00000062064
UniProt Q6PXP3 B1ARZ3
RefSeq (mRNA) NM_207420 NM_001085529.1
RefSeq (protein) NP_997303 NP_001078998.1
Location (UCSC) Chr 1:
9.06 – 9.09 Mb		 Chr 4:
149.52 – 149.54 Mb
PubMed search [1] [2]

Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene.[1][2]

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.[2] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.[3]

See also

References

  1. ^ "Entrez Gene: solute carrier family 2 (facilitated glucose transporter)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=155184. 
  2. ^ a b Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI (July 2004). "Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (1): G236–42. doi:10.1152/ajpgi.00396.2003. PMID 15033637. 
  3. ^ Joost HG, Thorens B (2001). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol. Membr. Biol. 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753. 

Further reading

  • Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI (2005). "Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).". J. Biol. Chem. 280 (52): 42978–83. doi:10.1074/jbc.M508678200. PMID 16186102.