Pulmonary surfactant-associated protein A1

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Surfactant protein A1

Identifiers

SFTPA1; COLEC4; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; MGC198590; PSAP; PSP-A; PSPA; SFTP1; SFTPA1B; SP-A; SP-A1; SPA; SPA1

External IDs

OMIM: 178630 HomoloGene: 3946 GeneCards: SFTPA1 Gene

Gene Ontology
Molecular function	• lipid transporter activity • binding • sugar binding
Cellular component	• extracellular region • collagen • extracellular space
Biological process	• lipid transport • respiratory gaseous exchange • cell junction assembly
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

n/a

n/a

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

n/a

Chr 14:
41.95 – 41.95 Mb

PubMed search

[1]

[2]

Pulmonary surfactant-associated protein A1, also known as SFTPA1, is a human gene.

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Floros J, Hoover RR (1999). "Genetics of the hydrophilic surfactant proteins A and D.". Biochim. Biophys. Acta 1408 (2-3): 312–22. doi:10.1016/S0925-4439(98)00077-5. PMID 9813381.
Khubchandani KR, Snyder JM (2001). "Surfactant protein A (SP-A): the alveolus and beyond.". FASEB J. 15 (1): 59–69. doi:10.1096/fj.00-0318rev. PMID 11149893.
Katyal SL, Singh G, Locker J (1992). "Characterization of a second human pulmonary surfactant-associated protein SP-A gene.". Am. J. Respir. Cell Mol. Biol. 6 (4): 446–52. PMID 1372511.
Childs RA, Wright JR, Ross GF, et al. (1992). "Specificity of lung surfactant protein SP-A for both the carbohydrate and the lipid moieties of certain neutral glycolipids.". J. Biol. Chem. 267 (14): 9972–9. PMID 1577827.
Endo H, Oka T (1991). "An immunohistochemical study of bronchial cells producing surfactant protein A in the developing human fetal lung.". Early Hum. Dev. 25 (3): 149–56. doi:10.1016/0378-3782(91)90111-F. PMID 1935736.
Voss T, Melchers K, Scheirle G, Schäfer KP (1991). "Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: implications for the chain composition of natural human SP-A.". Am. J. Respir. Cell Mol. Biol. 4 (1): 88–94. PMID 1986781.
Haagsman HP, White RT, Schilling J, et al. (1990). "Studies of the structure of lung surfactant protein SP-A.". Am. J. Physiol. 257 (6 Pt 1): L421–9. PMID 2610270.
Fisher JH, Kao FT, Jones C, et al. (1987). "The coding sequence for the 32,000-dalton pulmonary surfactant-associated protein A is located on chromosome 10 and identifies two separate restriction-fragment-length polymorphisms.". Am. J. Hum. Genet. 40 (6): 503–11. PMC 1684155. PMID 2884868. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1684155.
White RT, Damm D, Miller J, et al. (1985). "Isolation and characterization of the human pulmonary surfactant apoprotein gene.". Nature 317 (6035): 361–3. doi:10.1038/317361a0. PMID 2995821.
Floros J, Steinbrink R, Jacobs K, et al. (1986). "Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.". J. Biol. Chem. 261 (19): 9029–33. PMID 3755136.
Schaeffer E, Guillou F, Part D, Zakin MM (1993). "A different combination of transcription factors modulates the expression of the human transferrin promoter in liver and Sertoli cells.". J. Biol. Chem. 268 (31): 23399–408. PMID 8226864.
Khoor A, Gray ME, Hull WM, et al. (1993). "Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn.". J. Histochem. Cytochem. 41 (9): 1311–9. PMID 8354874.
Strayer DS, Yang S, Jerng HH (1993). "Surfactant protein A-binding proteins. Characterization and structures.". J. Biol. Chem. 268 (25): 18679–84. PMID 8360162.
Kölble K, Lu J, Mole SE, et al. (1993). "Assignment of the human pulmonary surfactant protein D gene (SFTP4) to 10q22-q23 close to the surfactant protein A gene cluster.". Genomics 17 (2): 294–8. doi:10.1006/geno.1993.1324. PMID 8406480.
deMello DE, Heyman S, Phelps DS, Floros J (1993). "Immunogold localization of SP-A in lungs of infants dying from respiratory distress syndrome.". Am. J. Pathol. 142 (5): 1631–40. PMC 1886897. PMID 8494055. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1886897.
Chroneos ZC, Abdolrasulnia R, Whitsett JA, et al. (1996). "Purification of a cell-surface receptor for surfactant protein A.". J. Biol. Chem. 271 (27): 16375–83. doi:10.1074/jbc.271.27.16375. PMID 8663107.
Planer BC, Ning Y, Kumar SA, Ballard PL (1997). "Transcriptional regulation of surfactant proteins SP-A and SP-B by phorbol ester.". Biochim. Biophys. Acta 1353 (2): 171–9. PMID 9294011.

Pulmonary surfactant-associated protein A1

See also

Further reading