SERTAD1

SERTA domain containing 1
Identifiers
Symbols SERTAD1; SEI1; TRIP-Br1
External IDs MGI1913438 HomoloGene8365 GeneCards: SERTAD1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 29950 55942
Ensembl ENSG00000197019 ENSMUSG00000008384
UniProt Q9UHV2 Q9JL10
RefSeq (mRNA) NM_013376 NM_018820.4
RefSeq (protein) NP_037508 NP_061290.1
Location (UCSC) Chr 19:
40.93 – 40.93 Mb
Chr 7:
28.27 – 28.28 Mb
PubMed search [1] [2]

SERTA domain-containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene.[1][2][3]

Interactions

SERTAD1 has been shown to interact with P16,[4][2] Cyclin-dependent kinase 4[4][2] and CREB-binding protein.[5]

References

  1. ^ Besley GT, Broadhead DM, Lawlor E (Nov 1984). "Acid esterase deficiency: comparison of biochemical findings in infantile and adult forms". J Inherit Metab Dis 7 Suppl 2: 155–6. PMID 6434876. 
  2. ^ a b c Sugimoto M, Nakamura T, Ohtani N, Hampson L, Hampson IN, Shimamoto A, Furuichi Y, Okumura K, Niwa S, Taya Y, Hara E (Jan 2000). "Regulation of CDK4 activity by a novel CDK4-binding protein, p34SEI-1". Genes Dev 13 (22): 3027–33. doi:10.1101/gad.13.22.3027. PMC 317153. PMID 10580009. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=317153. 
  3. ^ "Entrez Gene: SERTAD1 SERTA domain containing 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29950. 
  4. ^ a b Li, Junan; Melvin W Scott, Tsai Ming-Daw, Muscarella Peter (Apr. 2004). "The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner". Biochemistry (United States) 43 (14): 4394–9. doi:10.1021/bi035601s. ISSN 0006-2960. PMID 15065884. 
  5. ^ Hirose, Takuji; Fujii Ryouji, Nakamura Hiroshi, Aratani Satoko, Fujita Hidetoshi, Nakazawa Minako, Nakamura Kohzo, Nishioka Kusuki, Nakajima Toshihiro (Jun. 2003). "Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP". Int. J. Mol. Med. (Greece) 11 (6): 705–12. ISSN 1107-3756. PMID 12736710. 

Further reading