SELENBP1

Selenium binding protein 1
Identifiers
Symbols SELENBP1; FLJ13813; LPSB; SBP56; SP56; hSBP; hSP56
External IDs OMIM604188 MGI96825 HomoloGene2930 GeneCards: SELENBP1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 8991 20341
Ensembl ENSG00000143416 ENSMUSG00000068874
UniProt Q13228 Q91X87
RefSeq (mRNA) NM_003944 NM_009150.3
RefSeq (protein) NP_003935 NP_033176.2
Location (UCSC) Chr 1:
151.34 – 151.35 Mb
Chr 3:
94.74 – 94.75 Mb
PubMed search [1] [2]

Selenium-binding protein 1 is a protein that in humans is encoded by the SELENBP1 gene.[1][2]

This gene product belongs to the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. It has been proposed that the effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins. The exact function of this gene is not known.[2]

Interactions

SELENBP1 has been shown to interact with USP33.[3]

References

  1. ^ Chang PW, Tsui SK, Liew C, Lee CC, Waye MM, Fung KP (Apr 1997). "Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein". J Cell Biochem 64 (2): 217–24. doi:10.1002/(SICI)1097-4644(199702)64:2<217::AID-JCB5>3.0.CO;2-#. PMID 9027582. 
  2. ^ a b "Entrez Gene: SELENBP1 selenium binding protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8991. 
  3. ^ Jeong, Jee-Yeong; Wang Yuxun, Sytkowski Arthur J (Feb. 2009). "Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner". Biochem. Biophys. Res. Commun. (United States) 379 (2): 583–8. doi:10.1016/j.bbrc.2008.12.110. PMID 19118533. 

Further reading