Rifampicin/isoniazid/pyrazinamide

Rifampicin/isoniazid/pyrazinamide
Combination of
Rifampicin Rifamycin antibiotic
Isoniazid First-line anti-tuberculosis medication
Pyrazinamide Anti-tuberculosis medication
Clinical data
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral
Identifiers
ATC code J04AM05
ChemSpider 10468813 Y
 Y(what is this?)  (verify)

Rifater is a fixed dose combination tablet manufactured by Aventis used in the treatment of tuberculosis. Each tablet contains 120 mg rifampicin, 50 mg isoniazid and 300 mg pyrazinamide.

It is used in the first two months of tuberculosis treatment. The dose given depends on the patient's weight:

Rifater should not be used in children (the doses are wrong for them).

The purpose of the fixed dose combination is to make it easier for patients to take their medication; but also to ensure that if patients forget to take one or two of their drugs, they do not then develop resistance to the remaining drugs.

See also