Quinaldine

Quinaldine
IUPAC name

2-Methylquinoline
Other names

Quinaldine, α-methylquinoline, chinaldine, khinaldin
Identifiers
CAS number 91-63-4 Y
PubChem 7060
ChemSpider 13870160 Y
EC number 202-085-1
ChEMBL CHEMBL194931 N
Jmol-3D images Image 1
Properties
Molecular formula C10H9N
Molar mass 143.19 g/mol
Appearance Clear to yellow oily liquid
Density 1.058 g/cm3
Melting point

-2 °C, 271 K, 28 °F
Boiling point

248 °C, 521 K, 478 °F
Solubility in water Insoluble
Hazards
R-phrases R21/22 R34
Main hazards Harmful (Xn), Corrosive (C)
NFPA 704
2
2
0
Flash point 79 °C
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Quinaldine or 2-methylquinoline is a simple derivative of a heterocyclic compound quinoline.

Quinaldine has critical point at 787 K and 4.9 MPa and its refractive index is 1.8116.

It can be prepared from aniline and paraldehyde via Skraup synthesis or from aniline and crotonaldehyde via Doebner-von Miller variation of the Skraup reaction[1] or extracted from coal tar.

Uses

Quinaldine is used in anti-malaria drugs, in manufacturing dyes, food colorants (e.g. Quinoline Yellow WS), pharmaceuticals, pH indicators.

Quinaldine sulfate is an anaesthetic used in fish transportation.[2] In some Caribbean islands it is used to facilitate the collection of tropical fish from reefs.

References

  1. ^ Classical methods of synthesizing quinolines
  2. ^ Blasiola G. C. Jr. (1977). "Quinaldine sulphate, a new anaesthetic formulation for tropical marine fishes". Journal of Fish Biology 10 (2): 113–119(7). doi:10.1111/j.1095-8649.1977.tb04048.x. http://www.blackwell-synergy.com/doi/abs/10.1111/j.1095-8649.1977.tb04048.x. Retrieved 2007-07-16. 

External links