Propiconazole

Propiconazole[1]
IUPAC name

1-[ [2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole
Identifiers
CAS number 60207-90-1 Y
PubChem 43234
ChemSpider 39402 Y
UNII 142KW8TBSR Y
KEGG C11121 Y
ChEBI CHEBI:8489 Y
ChEMBL CHEMBL560579 Y
Jmol-3D images Image 1
Properties
Molecular formula C15H17Cl2N3O2
Molar mass 342.22038
Boiling point

180 °C at 0.1 mmHg [1]
Solubility in water 100 ppm at 20 °C
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Propiconazole is a triazole fungicide, also known as a DMI, or demethylation inhibiting fungicide due to its binding with and inhibiting the 14-alpha demethylase enzyme from demethylating a precursor to ergosterol. Without this demethylation step, the ergosterols are not incorporated into the growing fungal cell walls, and cellular growth is stopped. Propiconazole is used agriculturally on turfgrasses grown for seed and asthetic or athletic value, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes.[2] Propiconazole is a mixture[3] of four stereoisomers and was first developed in 1979 by Janssen Pharmaceutica.[4]

References

  1. ^ Merck Index, 11th Edition, 7830.
  2. ^ EXTOXNET
  3. ^ L. Toribio, M. J. del Nozal, J. L. Bernal, J. J. Jeménez und C. Alonso, J. Chromatography A 2004, 1046, 249-253.
  4. ^ W. T. Thomson. 1997. Agricultural Chemicals. Book IV: Fungicides. 12th edition. Thomson Publications, Fresno, CA

External links