Pregnanetriol

Pregnanetriol

IUPAC name (3R,5R,8R,9S,10S,13S,14S,17R)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
Other names 5β-Pregnane-3α,17α,20α-triol
Identifiers
CAS number	1098-45-9
PubChem	101967
ChemSpider	92121^Y
Jmol-3D images	Image 1
SMILES O[C@H]4C[C@@H]3[C@]([C@@H]1[C@H]([C@H]2[C@](C)(CC1)[C@@](O)([C@@H](O)C)CC2)CC3)(C)CC4
InChI InChI=1S/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13-,14+,15+,16+,17-,18-,19-,20-,21-/m0/s1^Y Key: SCPADBBISMMJAW-UHHUKTEYSA-N^Y InChI=1/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13-,14+,15+,16+,17-,18-,19-,20-,21-/m0/s1 Key: SCPADBBISMMJAW-UHHUKTEYBG
Properties
Molecular formula	C₂₁H₃₆O₂
Molar mass	320.51 g mol⁻¹
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pregnanetriol is a steroid.

Urine testing

Urine excretion of pregnanetriol can be measured over a period of 24 hours. Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with cortisol replacement, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.^[1]

Reference ranges

For females:^[1]

0 to 5 years: < 0.1 mg/24 hours
6 to 9 years: < 0.3 mg/24 hours
10 to 15 years: 0.1 to 0.6 mg/24 hours
16 years and older: 0 to 1.4 mg/ 24 hours.

For males:^[1]

0 to 5 years: < 0.1 mg/24 hours
6 to 9 years: < 0.3 mg/24 hours
10 to 15 years: 0.2 to 0.6 mg/24 hours
16 years and older: 0.2 to 2 mg/ 24 hours

References

^ ^a ^b ^c online-family-doctor.com Pregnanetriol Retrieved April 2011