Porcelain gallbladder

Porcelain gallbladder
Classification and external resources

Porcelain gallbladder on X-ray
ICD-9 575.8
eMedicine radio/569

Porcelain gallbladder is a calcification of the gallbladder believed to be brought on by excessive gallstones, although the exact cause is not clear. As with gallstone disease in general, this condition occurs predominantly in overweight female patients of middle age. It is a morphological variant of chronic cholecystitis. Inflammatory scarring of the wall, combined with dystrophic calcification within the wall transforms the gallbladder into a porcelain-like vessel.

Contents

Association with cancer

Porcelain gallbladder is associated with gallbladder cancer, but the precise nature of the association is uncertain. Two review articles examined the association between cancer of the gallbladder and calcified gallbladder. One study reported an incidence of gallbladder cancer of about 1% in patients with calcified gallbladder. .Another study found that of 69 calcified gallbladders, 3 of them contained cancer.[1][2]

Symptoms

Symptoms can include abdominal pain (especially after eating), jaundice, and vomiting. First symptom to appear is Jaundice followed by Right upper quadrant pain.

Diagnosis

Abdominal radiography (X-ray), abdominal ultrasound or CT scan.

Treatment

Recommended treatment is surgical removal of the gallbladder, although laparoscopic cholecystectomy is contraindicated in this case because of fear of seeding of cancer cells in the trochar sites.

References

  1. ^ Towfigh S, McFadden DW, Cortina GR, et al. (2001). "Porcelain gallbladder is not associated with gallbladder carcinoma". The American surgeon 67 (1): 7–10. PMID 11206901. 
  2. ^ Stephen AE, Berger DL (2001). "Carcinoma in the porcelain gallbladder: a relationship revisited". Surgery 129 (6): 699–703. doi:10.1067/msy.2001.113888. PMID 11391368. 

External links