PSTPIP1
Proline-serine-threonine phosphatase-interacting protein 1 is an enzyme that in humans is encoded by the PSTPIP1 gene.[1][2]
Interactions
PSTPIP1 has been shown to interact with PTPN12,[3] PTPN18,[4] BZW1,[5] Abl gene,[6] Wiskott-Aldrich syndrome protein[7] and CD2.[1]
See also
References
- ^ a b Li J, Nishizawa K, An W, Hussey RE, Lialios FE, Salgia R, Sunder-Plassmann R, Reinherz EL (Feb 1999). "A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion". EMBO J 17 (24): 7320–36. doi:10.1093/emboj/17.24.7320. PMC 1171078. PMID 9857189. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1171078.
- ^ "Entrez Gene: PSTPIP1 proline-serine-threonine phosphatase interacting protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9051.
- ^ Dowbenko, D; Spencer S, Quan C, Lasky L A (Jan. 1998). "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein". J. Biol. Chem. (UNITED STATES) 273 (2): 989–96. doi:10.1074/jbc.273.2.989. ISSN 0021-9258. PMID 9422760.
- ^ Spencer, S; Dowbenko D, Cheng J, Li W, Brush J, Utzig S, Simanis V, Lasky L A (Aug. 1997). "PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase". J. Cell Biol. (UNITED STATES) 138 (4): 845–60. doi:10.1083/jcb.138.4.845. ISSN 0021-9525. PMC 2138048. PMID 9265651. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2138048.
- ^ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.
- ^ Cong, F; Spencer S, Côté J F, Wu Y, Tremblay M L, Lasky L A, Goff S P (Dec. 2000). "Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation". Mol. Cell (United States) 6 (6): 1413–23. doi:10.1016/S1097-2765(00)00138-6. ISSN 1097-2765. PMID 11163214.
- ^ Wu, Y; Spencer S D, Lasky L A (Mar. 1998). "Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein". J. Biol. Chem. (UNITED STATES) 273 (10): 5765–70. doi:10.1074/jbc.273.10.5765. ISSN 0021-9258. PMID 9488710.
Further reading
- Spencer S, Dowbenko D, Cheng J, et al. (1997). "PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase.". J. Cell Biol. 138 (4): 845–60. doi:10.1083/jcb.138.4.845. PMC 2138048. PMID 9265651. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2138048.
- Dowbenko D, Spencer S, Quan C, Lasky LA (1998). "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein.". J. Biol. Chem. 273 (2): 989–96. doi:10.1074/jbc.273.2.989. PMID 9422760.
- Wu Y, Spencer SD, Lasky LA (1998). "Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein.". J. Biol. Chem. 273 (10): 5765–70. doi:10.1074/jbc.273.10.5765. PMID 9488710.
- Wu Y, Dowbenko D, Lasky LA (1998). "PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase.". J. Biol. Chem. 273 (46): 30487–96. doi:10.1074/jbc.273.46.30487. PMID 9804817.
- Cong F, Spencer S, Côté JF, et al. (2001). "Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation.". Mol. Cell 6 (6): 1413–23. doi:10.1016/S1097-2765(00)00138-6. PMID 11163214.
- Oda A, Ochs HD, Lasky LA, et al. (2001). "CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.". Blood 97 (9): 2633–9. doi:10.1182/blood.V97.9.2633. PMID 11313252.
- Côté JF, Chung PL, Théberge JF, et al. (2002). "PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP.". J. Biol. Chem. 277 (4): 2973–86. doi:10.1074/jbc.M106428200. PMID 11711533.
- Wise CA, Gillum JD, Seidman CE, et al. (2003). "Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder.". Hum. Mol. Genet. 11 (8): 961–9. doi:10.1093/hmg/11.8.961. PMID 11971877.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Badour K, Zhang J, Shi F, et al. (2003). "The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse.". Immunity 18 (1): 141–54. doi:10.1016/S1074-7613(02)00516-2. PMID 12530983.
- Shoham NG, Centola M, Mansfield E, et al. (2004). "Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway.". Proc. Natl. Acad. Sci. U.S.A. 100 (23): 13501–6. doi:10.1073/pnas.2135380100. PMC 263843. PMID 14595024. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=263843.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Baum W, Kirkin V, Fernández SB, et al. (2006). "Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.". J. Biol. Chem. 280 (48): 40012–24. doi:10.1074/jbc.M502222200. PMID 16204241.
- Yang H, Reinherz EL (2006). "CD2BP1 modulates CD2-dependent T cell activation via linkage to protein tyrosine phosphatase (PTP)-PEST.". J. Immunol. 176 (10): 5898–907. PMID 16670297.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.
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PDB gallery
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2dil: Solution structure of the SH3 domain of the human Proline-serine-threonine phosphatase-interacting protein 1
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