PLXNA3

Plexin A3

Identifiers

PLXNA3; 6.3; HSSEXGENE; PLEXIN-A3; PLXN3; PLXN4; SEX; XAP-6

External IDs

OMIM: 300022 MGI: 107683 HomoloGene: 7481 GeneCards: PLXNA3 Gene

Gene Ontology
Molecular function	• transmembrane receptor activity
Cellular component	• intracellular • plasma membrane • plasma membrane • membrane • integral to membrane
Biological process	• signal transduction • multicellular organismal development • axon guidance
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

n/a

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr X:
153.69 – 153.7 Mb

Chr X:
71.57 – 71.59 Mb

PubMed search

[1]

[2]

Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene.^[1]^[2]^[3]

References

^ Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D (Jan 1994). "Transcriptional organization of a 450-kb region of the human X chromosome in Xq28". Proc Natl Acad Sci U S A 90 (23): 10977–81. doi:10.1073/pnas.90.23.10977. PMC 47904. PMID 8248200. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=47904.
^ Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.
^ "Entrez Gene: PLXNA3 plexin A3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55558.

Sedlacek Z, Korn B, Konecki DS et al. (1994). "Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection". Hum. Mol. Genet. 2 (11): 1865–9. doi:10.1093/hmg/2.11.1865. PMID 8281148.
Maestrini E, Tamagnone L, Longati P et al. (1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc. Natl. Acad. Sci. U.S.A. 93 (2): 674–8. doi:10.1073/pnas.93.2.674. PMC 40111. PMID 8570614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=40111.
Kameyama T, Murakami Y, Suto F et al. (1996). "Identification of plexin family molecules in mice". Biochem. Biophys. Res. Commun. 226 (2): 396–402. doi:10.1006/bbrc.1996.1367. PMID 8806646.
Tamagnone L, Artigiani S, Chen H et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell 99 (1): 71–80. doi:10.1016/S0092-8674(00)80063-X. PMID 10520995.
Dias Neto E, Correa RG, Verjovski-Almeida S et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=16267.
Brandenberger R, Wei H, Zhang S et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Fu GK, Wang JT, Yang J et al. (2005). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.

PLXNA3

References

Further reading