PCDH1

Protocadherin 1
Identifiers
Symbols PCDH1; FLJ53887; MGC45991; PC42; PCDH42
External IDs OMIM603626 MGI104692 HomoloGene12613 GeneCards: PCDH1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 5097 75599
Ensembl ENSG00000156453 ENSMUSG00000051375
UniProt Q08174 n/a
RefSeq (mRNA) NM_002587.3 NM_029357.3
RefSeq (protein) NP_002578.2 NP_083633.2
Location (UCSC) Chr 5:
141.23 – 141.26 Mb
Chr 18:
38.35 – 38.37 Mb
PubMed search [1] [2]

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.[1][2]

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.[2]

References

Further reading