Monoclonal antibody | |
---|---|
Type | Single-chain variable fragment |
Source | Humanized |
Target | EpCAM |
Clinical data | |
Pregnancy cat. | ? |
Legal status | ? |
Identifiers | |
CAS number | 945228-48-8 |
ATC code | None |
Chemical data | |
Formula | C3072H4723N877O952S12 |
Mol. mass | 69.6 kDa |
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(what is this?)
Oportuzumab monatox (proposed INN) is an antineoplastic. Chemically, oportuzumab it is a single chain variable fragment of a monoclonal antibody which binds to epithelial cell adhesion molecule (EpCAM, the tumor-associated calcium signal transducer 1). Oportuzumab is fused with Pseudomonas aeruginosa exotoxin A (which is reflected by the monatox in the drug's name).[1]