Oesyme or Oisyme (Ancient Greek: Οίσύμη) or (Ancient Greek: Οίσύμα) or (Ancient Greek: Αίσύμη) was an ancient Greek[1] polis located in Thrace , located in the region between the river Strymon and the river Nestos. It was founded by colonists from Thasos perhaps at 650 BC.It was later renamed (Ancient Greek: Ημαθία) after its occupation by Phillip II of Macedon.It was considered a polis and an emporion at the same time.It is the only city of the Thasian peraia mentioned by Homer (as Ancient Greek: Αίσύμη).Oisyme joined[2] Brasidas after he captured Amphipolis along with Myrkinos and Galepsus.
The location of the ancient city is identified with the fortified citadel on cape Vrasidas south of the village of Nea Peramos in the southern part of the bay of Eleutherai.