OFC

OFC may refer to:

• Corporate Office Properties Trust (ticker symbol)
• Oceania Football Confederation
• Offshore Financial Centre
• Online Film Critics Society
• Open fiber control
• Open Financial Connectivity
• Optical fiber cable
• Optical Fiber Conference
• Optional federal charter, a proposal to streamline and simplify US insurance regulation
• Orbitofrontal cortex, a region of the brain involved in decision making and other cognitive functions
• Occipito-frontal head circumference, abbreviation used in scientific articles
• Osteitis fibrosa cystica, a skeletal disease involving the parathyroid glands
• Ottawa Folklore Centre
• Oxygen-free copper, a copper cable manufacturing process
• ofc, an SMS language abbreviation for "of course"
• Oxy-fuel cutting, a metal cutting process