Norgestimate

Norgestimate

Systematic (IUPAC) name
(13-ethyl-17-ethynyl-3-hydroxyimino- 1,2,6,7,8,9,10,11,12,14,15,16- dodecahydrocyclopenta[a] phenanthren-17-yl) acetate
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a601050
Pregnancy cat.	?
Legal status	?
Pharmacokinetic data
Half-life	12-30 hours
Identifiers
CAS number	35189-28-7^Y
ATC code	G03AA11
PubChem	CID 6540478
DrugBank	APRD00569
ChemSpider	5022837^Y
UNII	C291HFX4DY^Y
KEGG	D05209^Y
ChEBI	CHEBI:50815^Y
ChEMBL	CHEMBL1200934^N
Chemical data
Formula	C₂₃H₃₁N O₃
Mol. mass	369.497 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C23H31NO3/c1-4-22-12-10-19-18-9-7-17(24-26)14-16(18)6-8-20(19)21(22)11-13-23(22,5-2)27-15(3)25/h2,14,18-21,26H,4,6-13H2,1,3H3/b24-17+/t18-,19+,20+,21-,22-,23-/m0/s1^Y Key:KIQQMECNKUGGKA-NMYWJIRASA-N^Y
N(what is this?) (verify)

Norgestimate is a molecule used in hormonal contraceptives.

Norgestimate is a form of progesterone, which is a female hormone important for the regulation of ovulation and menstruation. Norgestimate is used with estradiol (a female sex hormone that is involved in the development and maintenance of the female reproductive system), to treat the symptoms of menopause.

1st	Norpregnene (Norethisterone^#/Norethisterone acetate • Ethynodiol diacetate)

2nd	Norpregnene (Levonorgestrel^#/Norgestrel/Norelgestromin)

3rd	19-nortestosterone (Desogestrel/Etonogestrel • Gestodene • Norgestimate)

4th	Androstene (Drospirenone) • 19-norprogesterone (Nomegestrol • Promegestone • Trimegestone) • 19-nortestosterone (Dienogest)

17-OH	Chlormadinone • Cyproterone • Medroxyprogesterone/Medroxyprogesterone 17-acetate^# • Megestrol

Other/ ungrouped	Pregnenedione (Gestonorone) • Pregnene (Ethisterone) • Pregnadiene (Medrogestone • Melengestrol) • Norpregnane (Norgestrienone) • Lynestrenol • Norethynodrel • Tibolone • Dydrogesterone • Quingestanol

Antiprogestin/
SPRM

antagonist: Mifepristone

Asoprisnil • CDB-4124 • Ulipristal acetate

Estrogens

Agonist

Steroidal	Diosgenin • Estradiol (Ethinylestradiol^#/Mestranol • Estradiol 17 beta-cypionate^# • Polyestradiol phosphate) • Estrone (Estrone sulfate) • Estriol • Promestriene • Equilenin • Equilin

Nonsteroidal	Chlorotrianisene • Dienestrol • Fosfestrol • Diethylstilbestrol • Zeranol

Antiestrogen/
SERM

Afimoxifene • Arzoxifene • Bazedoxifene • Cyclofenil • Lasofoxifene • Ormeloxifene • Raloxifene • Tamoxifen • Toremifene

Clomifene^# • Mepitiostane • Nafoxidine

pure antagonist: Fulvestrant

Aromatase inhibitors

nonselective: Aminoglutethimide • Testolactone

selective: Anastrozole • Atamestane • Exemestane • Fadrozole • Formestane • Letrozole • Vorozole

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)

Norgestimate

See also