Nomegestrol

Nomegestrol

IUPAC name (8S,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,13-dimethyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Other names Monaco; TX 071; Thermex
Identifiers
CAS number	58691-88-6
PubChem	68783
ChemSpider	62024^Y
KEGG	D07222^Y
Jmol-3D images	Image 1
SMILES O=C4\C=C3\C(=C/[C@@H]1[C@H](CC[C@@]2([C@@](O)(C(=O)C)CC[C@@H]12)C)[C@H]3CC4)C
InChI InChI=1S/C21H28O3/c1-12-10-18-16(15-5-4-14(23)11-17(12)15)6-8-20(3)19(18)7-9-21(20,24)13(2)22/h10-11,15-16,18-19,24H,4-9H2,1-3H3/t15-,16-,18-,19+,20+,21+/m1/s1^Y Key: KZUIYQJTUIACIG-YBZCJVABSA-N^Y InChI=1/C21H28O3/c1-12-10-18-16(15-5-4-14(23)11-17(12)15)6-8-20(3)19(18)7-9-21(20,24)13(2)22/h10-11,15-16,18-19,24H,4-9H2,1-3H3/t15-,16-,18-,19+,20+,21+/m1/s1 Key: KZUIYQJTUIACIG-YBZCJVABBM
Properties
Molecular formula	C₂₁H₂₈O₃
Molar mass	328.44522
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nomegestrol is a progestogen.

Estrogens and progestogens (G03C-D, L02)

Progestogens/
progestins
(progesterone)

Agonist

1st	Norpregnene (Norethisterone^#/Norethisterone acetate • Ethynodiol diacetate)

2nd	Norpregnene (Levonorgestrel^#/Norgestrel/Norelgestromin)

3rd	19-nortestosterone (Desogestrel/Etonogestrel • Gestodene • Norgestimate)

4th	Androstene (Drospirenone) • 19-norprogesterone (Nomegestrol • Promegestone • Trimegestone) • 19-nortestosterone (Dienogest)

17-OH	Chlormadinone • Cyproterone • Medroxyprogesterone/Medroxyprogesterone 17-acetate^# • Megestrol

Other/ ungrouped	Pregnenedione (Gestonorone) • Pregnene (Ethisterone) • Pregnadiene (Medrogestone • Melengestrol) • Norpregnane (Norgestrienone) • Lynestrenol • Norethynodrel • Tibolone • Dydrogesterone • Quingestanol

Antiprogestin/
SPRM

antagonist: Mifepristone

Asoprisnil • CDB-4124 • Ulipristal acetate

Agonist

Steroidal	Diosgenin • Estradiol (Ethinylestradiol^#/Mestranol • Estradiol 17 beta-cypionate^# • Polyestradiol phosphate) • Estrone (Estrone sulfate) • Estriol • Promestriene • Equilenin • Equilin

Nonsteroidal	Chlorotrianisene • Dienestrol • Fosfestrol • Diethylstilbestrol • Zeranol

Antiestrogen/
SERM

Afimoxifene • Arzoxifene • Bazedoxifene • Cyclofenil • Lasofoxifene • Ormeloxifene • Raloxifene • Tamoxifen • Toremifene

Clomifene^# • Mepitiostane • Nafoxidine

pure antagonist: Fulvestrant

Aromatase inhibitors

nonselective: Aminoglutethimide • Testolactone

selective: Anastrozole • Atamestane • Exemestane • Fadrozole • Formestane • Letrozole • Vorozole

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)