Neoflavonoid

Neoflavonoids are a class of polyphenolic compounds^[1]. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2.

Types

Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols.

• Neoflavones^[2] are derived from the 4-phenylcoumarin (or 4-Aryl-coumarin) backbone (C₁₅H₁₂O₂, molar mass : 224.25g/mol, exact mass : 224.083729)^[3]. The first neoflavone isolated from natural sources in 1951 was calophyllolide from Calophyllum inophyllum seeds^[4].
• Neoflavenes possess the 4-phenylchromen backbone (chemical formula : C₁₅H₁₀O₂, exact mass : 222.0680792). Dalbergichromene, extracted from the stem-bark and heartwood of Dalbergia sissoo, is an example of such compounds^[5]

Other examples

• Coutareagenin (5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzo-1-pyran-2-on) found in Hintonia latiflora^[6]
• Dalbergin
• Nivetin isolated from Echinops niveus^[7]

References

External links