NACHT and WD repeat domain containing 1 | |||||||||||
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Identifiers | |||||||||||
Symbols | NWD1; MGC134940 | ||||||||||
External IDs | MGI: 2442268 HomoloGene: 72261 GeneCards: NWD1 Gene | ||||||||||
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Orthologs | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | 284434 | 319555 | |||||||||
Ensembl | ENSG00000188039 | ENSMUSG00000048148 | |||||||||
UniProt | Q149M9 | A6H603 | |||||||||
RefSeq (mRNA) | NM_001007525 | NM_176940.5 | |||||||||
RefSeq (protein) | NP_001007526 | NP_795914.3 | |||||||||
Location (UCSC) | Chr 19: 16.83 – 16.93 Mb |
Chr 8: 75.17 – 75.24 Mb |
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PubMed search | [1] | [2] |
NWD1, short for NACHT and WD repeat domain containing 1, is a gene found in vertebrates, which encodes a protein that contains a NACHT domain and a WD40 repeat domain. It was originally identified during a search for immune system genes in zebrafish as a protein coding sequence related to APAF1; orthologs were subsequently identified in mammalian species.[1] The NWD1 gene of humans is located on chromosome 19. The function of the NWD1 protein is currently unknown.