NDUFA13

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 is an enzyme that in humans is encoded by the NDUFA13 gene.^[1]^[2]^[3]^[4]

Interactions

References

^ Hirst J, Carroll J, Fearnley IM, Shannon RJ, Walker JE (Jul 2003). "The nuclear encoded subunits of complex I from bovine heart mitochondria". Biochim Biophys Acta 1604 (3): 135–50. doi:10.1016/S0005-2728(03)00059-8. PMID 12837546.
^ Angell JE, Lindner DJ, Shapiro PS, Hofmann ER, Kalvakolanu DV (Nov 2000). "Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach". J Biol Chem 275 (43): 33416–26. doi:10.1074/jbc.M003929200. PMID 10924506.
^ Huang G, Lu H, Hao A, Ng DC, Ponniah S, Guo K, Lufei C, Zeng Q, Cao X (Sep 2004). "GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I". Mol Cell Biol 24 (19): 8447–56. doi:10.1128/MCB.24.19.8447-8456.2004. PMC 516758. PMID 15367666. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=516758.
^ "Entrez Gene: NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51079.
^ Zhang, Jun; Yang Jinbo, Roy Sanjit K, Tininini Silvia, Hu Jiadi, Bromberg Jacqueline F, Poli Valeria, Stark George R, Kalvakolanu Dhananjaya V (Aug. 2003). "The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3". Proc. Natl. Acad. Sci. U.S.A. (United States) 100 (16): 9342–7. doi:10.1073/pnas.1633516100. ISSN 0027-8424. PMC 170920. PMID 12867595. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=170920.

Further reading

Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310876.
Chidambaram NV, Angell JE, Ling W, et al. (2000). "Chromosomal localization of human GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death.". J. Interferon Cytokine Res. 20 (7): 661–5. doi:10.1089/107999000414844. PMID 10926209.
Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=16901.
Fearnley IM, Carroll J, Shannon RJ, et al. (2001). "GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I).". J. Biol. Chem. 276 (42): 38345–8. doi:10.1074/jbc.C100444200. PMID 11522775.
Seo T, Lee D, Shim YS, et al. (2002). "Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon/retinoic acid-induced cell death.". J. Virol. 76 (17): 8797–807. doi:10.1128/JVI.76.17.8797-8807.2002. PMC 136415. PMID 12163600. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=136415.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Murray J, Zhang B, Taylor SW, et al. (2003). "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.". J. Biol. Chem. 278 (16): 13619–22. doi:10.1074/jbc.C300064200. PMID 12611891.
Lufei C, Ma J, Huang G, et al. (2003). "GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction.". EMBO J. 22 (6): 1325–35. doi:10.1093/emboj/cdg135. PMC 151078. PMID 12628925. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151078.
Zhang J, Yang J, Roy SK, et al. (2003). "The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3.". Proc. Natl. Acad. Sci. U.S.A. 100 (16): 9342–7. doi:10.1073/pnas.1633516100. PMC 170920. PMID 12867595. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=170920.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=442147.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=515316.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Barnich N, Hisamatsu T, Aguirre JE, et al. (2005). "GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.". J. Biol. Chem. 280 (19): 19021–6. doi:10.1074/jbc.M413776200. PMID 15753091.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Huang G, Chen Y, Lu H, Cao X (2007). "Coupling mitochondrial respiratory chain to cell death: an essential role of mitochondrial complex I in the interferon-beta and retinoic acid-induced cancer cell death.". Cell Death Differ. 14 (2): 327–37. doi:10.1038/sj.cdd.4402004. PMID 16826196.
Vogel RO, Dieteren CE, van den Heuvel LP, et al. (2007). "Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits.". J. Biol. Chem. 282 (10): 7582–90. doi:10.1074/jbc.M609410200. PMID 17209039.