Dimethylacetamide

Dimethylacetamide
Identifiers
CAS number 127-19-5 Y
PubChem 31374
ChemSpider 29107 Y
UNII JCV5VDB3HY Y
ChEMBL CHEMBL11873 Y
RTECS number AB7700000
Jmol-3D images Image 1
Properties
Molecular formula C4H9NO
Molar mass 87.12 g mol−1
Appearance Colorless liquid with
faint ammonia odor
Density 0.94 g/cm3
Melting point

-20 °C, 253 K, -4 °F

Boiling point

164-166 °C

Viscosity 1.956 cP @ 25 °C

1.279 cP @ 50 °C
0.896 cP @ 75 °C
0.661 cP @ 100 °C

Hazards
R-phrases R61 R20/21
S-phrases S53 S45
Main hazards Toxic (T)
NFPA 704
0
2
0
Flash point 70 °C
Autoignition
temperature
490 °C
Related compounds
Related Compounds Acetic acid
Dimethylamine
Dimethylformamide
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dimethylacetamide is the organic compound with the formula CH3C(O)N(CH3)2. This colorless, water miscible, high boiling liquid is commonly used as a polar solvent in organic chemistry. DMAc is miscible with most other solvents, although it is poorly soluble in aliphatic hydrocarbons.

The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. It will hydrolyze in the presence of acids:

CH3CON(CH3)2 + H2O + HCl → CH3COOH + (CH3)2NH2+Cl-

Dimethylacetamide is useful as a medium for strong bases such as sodium hydroxide.[1] Dimethylacetamide is commonly used as a solvent for fibers or in the adhesive industry. It is also employed in the production of pharmaceuticals and plasticizers as a reaction medium.

References