Monokine

A monokine is a type of cytokine[1] produced primarily by monocytes and macrophages.

Examples include interleukin 1 and tumor necrosis factor-alpha.

Other monokines include alpha and beta interferon, and colony stimulating factors.[2]

Contents

Functions

Monokines released from macrophages can attract Neutrophils , via the process chemotaxis.

See also

References

  1. ^ MeSH Monokines
  2. ^ Julius M. Cruse; Robert Edwin Lewis (20 April 2009). Illustrated dictionary of immunology. CRC Press. pp. 208–. ISBN 9780849379871. http://books.google.com/books?id=X4X8d2SmQB0C&pg=PA208. Retrieved 24 April 2011. 

External links

By family
CCL
CCL1 · CCL2/MCP-1 · CCL3/MIP-1α · CCL4/MIP-1β · CCL5/RANTES · CCL6 · CCL7 · CCL8 · CCL9 · CCL11 · CCL12 · CCL13 · CCL14 · CCL15 · CCL16 · CCL17 · CCL18 · CCL19 · CCL20 · CCL21 · CCL22 · CCL23 · CCL24 · CCL25 · CCL26 · CCL27 · CCL28
CXCL
CXCL1/KC · CXCL2 · CXCL3 · CXCL4 · CXCL5 · CXCL6 · CXCL7 · CXCL8/IL8 · CXCL9 · CXCL10 · CXCL11 · CXCL12 · CXCL13 · CXCL14 · CXCL15 · CXCL16 · CXCL17
CX3CL
XCL
Type I
(grouped by
receptor
subunit)
IL2/IL15 · IL4/IL13 · IL7 · IL9 · IL21
IL3 · IL5 · GM-CSF
IL6 like/gp130
IL6  · IL11 · IL27 · IL30 · IL31 (+non IL OSM, LIF, CNTF, CTF1)
IL-12 family/IL12RB1
IL12 · IL23 · IL27 · IL35
Other
IL14 · IL16 · IL32  · IL34
Other
By function/
cell

proinflammatory cytokine (IL1, TNFA)

Monokine · Lymphokine (Th1 (IFNG and TNFB) · Th2 (IL4, IL5, IL6, IL10, IL13) )
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)