miraDry, is the trademark name[1] of a non-invasive microwave-based technology[2] for the treatment of axillary hyperhidrosis created by Miramar Labs[3] in 2003 and FDA Cleared in 2011.[4] Axillary hyperhidrosis, or excessive underarm sweat, is a medical condition where the sweat glands are overactive, producing more sweat than is needed to cool the body.[5]
miraDry is the first treatment option that destroys sweat glands in the axilla (underarms) without surgery, prescription medication or continual treatment for the patients lifespan.[6][7]
The treatment is currently offered in both the US and Japan.[8]
miraDry utilizes microwave energy, a form of electromagnetic energy, for the reduction or removal of sweat glands and hair follicles in the treatment of aesthetic, topical, and subcutaneous skin conditions. The current product use is for the treatment of axillary hyperhidrosis. For perspective, microwaves lie between radio frequency and lasers on the electromagnetic spectrum.[9] Microwave energy is suited to address hyperhidrosis because it can penetrate to the dermal-fat interface where sweat glands reside.[10]
Due to the microwave frequency chosen, device design, and the electromagnetic properties of skin and fat, constructive interference occurs and creates a Focal Energy Zone at the interface.[11] The energy generates heat which results in thermolysis of the sweat glands.
In parallel, a continuous hydro-ceramic cooling system protects the dermis while heat continues to spread down into the region where sweat glands reside, resulting in cellular thermolysis. Sweat glands do not regenerate,[12] so once destroyed, the excess sweat glands are permanently disabled.