Mibolerone

Mibolerone


Systematic (IUPAC) name
(7α,17β)-17-hydroxy-7,17-dimethylestr-4-en-3-one
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	Schedule 3 (US)
Routes	Oral
Pharmacokinetic data
Metabolism	Hepatic
Half-life	2-4 hours
Identifiers
CAS number	3704-09-4^N
ATC code	None
PubChem	CID 251636
ChemSpider	220460^Y
UNII	9OGY4BOR8D^Y
KEGG	D05025^Y
ChEMBL	CHEMBL425863^Y
Synonyms	(7R,8R,9S,10R,13S,14S,17S)-17-Hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Chemical data
Formula	C₂₀H₃₀O₂
Mol. mass	302.4558 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/m1/s1^Y Key:PTQMMNYJKCSPET-OMHQDGTGSA-N^Y
N(what is this?) (verify)

Mibolerone is a potent anabolic steroid which is both higher affinity^[1] and more selective^[2] for the androgen receptor than metribolone.

Under the brand name "Cheque Drops", Mibolerone was marketed as a veterinary drug by the Upjohn company. It was indicated as an oral treatment for estrous (heat) prevention in adult female dogs.

References

^ Murthy LR, Johnson MP, Rowley DR, Young CY, Scardino PT, Tindall DJ (1986). "Characterization of steroid receptors in human prostate using mibolerone". Prostate 8 (3): 241–53. doi:10.1002/pros.2990080305. PMID 2422638.
^ Schilling K, Liao S (1984). "The use of radioactive 7 alpha, 17 alpha-dimethyl-19-nortestosterone (mibolerone) in the assay of androgen receptors". Prostate 5 (6): 581–8. doi:10.1002/pros.2990050603. PMID 6333679.

Anabolic steroids (A14) (tradename in brackets)

Androstane (carbon 19 present)

Adrenosterone • Androisoxazole • Bolasterone (Myagen) • Bolazine • Boldione • Boldenone undecylenate (Equipoise) • 4-Chlordehydromethyltestosterone (Turinabol) • 4-Hydroxytestosterone • Calusterone • Clostebol • Danazol • Desoxymethyltestosterone (Madol) • DHT • Drostanolone (Masteron) • Enestebol • Epitiostanol • Fluoxymesterone (Halotestin) • Formebolone • Furazabol (Miotolan) • Hydroxystenozole • Mebolazine • Mesabolone • Mestanolone • Mesterolone (Proviron) • Methandriol • Methandrostenolone (Dianabol) • Methenolone • Methenolone enanthate (Primobolan) • Methasterone (Superdrol) • Methyltestosterone • Oxandrolone (Anavar) • Oxymetholone (Anadrol) • Oxymesterone • Prostanozol • Quinbolone (Anabolicum Vister) • Roxibolone • Silandrone • Stanozolol (Strombafort, Winstrol) • Stenbolone • Testosterone`s (Sustamed, Sustanon) • 1-Testosterone • Thiomesterone • Trestolone

Estrene (carbon 19 absent)

Bolenol • Ethyldienolone • Ethylestrenol • Mibolerone (Cheque Drops) • Methylnortestosterone • Metribolone (R1881) • Nandrolone (Deca Durabolin) • Norbolethone (Genabol) • Norclostebol • Norethandrolone • Normethandrone • Oxabolone cipionate • Propetandrol • Tetrahydrogestrinone (The Clear) • Trenbolone (Fina)

Prohormones

1-Androstenediol • 1,4-Androstadienedione • 4-Androstenediol • 4-Androstenedione • 19-Norandrostenediol • 19-Norandrostenedione • DHEA

M: DIG

anat(t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug(A2A/2B/3/4/5/6/7/14/16), blte