Methiodide

In organic chemistry, a methiodide is a chemical derivative produced by the reaction of a compound with methyl iodide. Methiodides may be formed through the methylation of amines:

R₃N + CH₃I → (CH₃)R₃N⁺I⁻

Methiodides are generally prepared to alter chemical or pharmacological properties. Examples include:

• Cocaine methiodide, a charged cocaine analog which cannot pass the blood brain barrier and enter the brain^[1]
• Bicuculline methiodide, a water-soluble form of bicuculline

References