"Me and My Uncle", often also written "Me & My Uncle," is a song composed by John Phillips of The Mamas & the Papas, and popularized by the Grateful Dead and Judy Collins. The song is set along the Goodnight-Loving Trail in the late 19th century.
John Phillips originally wrote "Me and My Uncle" at a drinking session in a hotel room with Judy Collins and Neil Young (among others) in 1963. According to Grateful Dead Lyric & Song Finder[1]
"Me and My Uncle" was first recorded by Judy Collins at some point in 1964, and performed at The Judy Collins Concert.
It was later heard by the Grateful Dead, who adopted it as one of their standard performances. Bob Weir is reported to have learned it from Curly Jim Cook, a member of the Bay Area A.B. Skhy Blues Band. According to Deadbase, the Grateful Dead first played the song in late 1966. The earliest commercially released performance of it is from the Electric Theater in Chicago, on April 26, 1969, and is available on Dick's Picks Volume 26. The song continued to be performed regularly until Jerry Garcia's death and the end of the band in 1995. According to Deadbase, it was the most-played song of all in the Dead's long concert career, with 616 performances.
Since the Grateful Dead disbanded in 1995, the song continues to be a staple of the surviving members' performances.
"Me and My Uncle" has also been performed by Joni (Anderson) Mitchell, John Denver, Dino Valente, Mike Wilhelm, Widespread Panic, Whisky Crick and by John Phillips himself.
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