Magnesium responsive RNA element

Magnesium responsive RNA element
Identifiers
Symbol Mg sensor
Rfam RF01056
Other data
RNA type Cis-regulatory element
Domain(s) Enterobacteriales
GO 0032026

The Magnesium responsive RNA element, not to be confused with the completely distinct M-box riboswitch, is a cis-regulatory element that regulates the expression of the magnesium transporter protein MgtA. It is located in the 5' UTR of this gene.[1] The mechanism for the potential magnesium-sensing capacity of this RNA is still unclear, though a recent report suggests that the RNA element targets the mgtA transcript for degradation by RNase E when cells are grown in high Mg2+ environments.[2]

References

  1. ^ Groisman EA, Cromie MJ, Shi Y, Latifi T (2006). "A Mg2+-responding RNA that controls the expression of a Mg2+ transporter.". Cold Spring Harb Symp Quant Biol 71: 251–8. doi:10.1101/sqb.2006.71.005. PMID 17381304. 
  2. ^ Spinelli SV, Pontel LB, García Véscovi E, Soncini FC (2008). "Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E.". FEMS Microbiol Lett 280 (2): 226–34. doi:10.1111/j.1574-6968.2008.01065.x. PMID 18248433. 

External links