MYO5B
Myosin-Vb is a protein that in humans is encoded by the MYO5B gene.[1][2][3]
Recent evidence suggests that Myosin VB is related to the creation of memories.[4]
Mutations of MYO5B causes microvillous inclusion disease.[5]
Interactions
MYO5B has been shown to interact with RAB11FIP2.[6]
References
- ^ Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (Feb 1997). "Mapping of unconventional myosins in mouse and human". Genomics 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
- ^ Swiatecka-Urban A, Talebian L, Kanno E, Moreau-Marquis S, Coutermarsh B, Hansen K, Karlson KH, Barnaby R, Cheney RE, Langford GM, Fukuda M, Stanton BA (Aug 2007). "Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells". J Biol Chem 282 (32): 23725–36. doi:10.1074/jbc.M608531200. PMID 17462998.
- ^ "Entrez Gene: MYO5B myosin VB". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4645.
- ^ "DukeHealth.org: Scientists Identify Machinery that Helps Make Memories". http://www.dukehealth.org/HealthLibrary/News/scientists_identify_machinery_that_helps_make_memories. Retrieved 2008-11-02.
- ^ Mueller T; Hess, MW; Schiefermeier, N; Pfaller, K; Ebner, HL; Heinz-Erian, P; Ponstingl, H; Partsch, J et al. (2008). "MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity". Nat Genet 40 (10): 1163–5. doi:10.1038/ng.225. PMID 18724368.
- ^ Hales, Chadwick M; Vaerman Jean-Pierre, Goldenring James R (Dec. 2002). "Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling". J. Biol. Chem. (United States) 277 (52): 50415–21. doi:10.1074/jbc.M209270200. ISSN 0021-9258. PMID 12393859.
Further reading
- Huang WM, Reed-Fourquet L, Wu E, Wu JY (1990). "Molecular cloning and amino acid sequence of brain L-glutamate decarboxylase". Proc. Natl. Acad. Sci. U.S.A. 87 (21): 8491–5. doi:10.1073/pnas.87.21.8491. PMC 54982. PMID 2236059. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=54982.
- Bement WM, Hasson T, Wirth JA, et al. (1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc. Natl. Acad. Sci. U.S.A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=44240.
- Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
- Lapierre LA, Kumar R, Hales CM, et al. (2001). "Myosin Vb Is Associated with Plasma Membrane Recycling Systems". Mol. Biol. Cell 12 (6): 1843–57. PMC 37346. PMID 11408590. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=37346.
- Hales CM, Griner R, Hobdy-Henderson KC, et al. (2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. PMID 11495908.
- Hales CM, Vaerman JP, Goldenring JR (2003). "Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling". J. Biol. Chem. 277 (52): 50415–21. doi:10.1074/jbc.M209270200. PMID 12393859.
- Nakayama M, Kikuno R, Ohara O (2003). "Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=187542.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Fan GH, Lapierre LA, Goldenring JR, et al. (2005). "Rab11-Family Interacting Protein 2 and Myosin Vb Are Required for CXCR2 Recycling and Receptor-mediated Chemotaxis". Mol. Biol. Cell 15 (5): 2456–69. doi:10.1091/mbc.E03-09-0706. PMC 404037. PMID 15004234. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=404037.
- Wakabayashi Y, Dutt P, Lippincott-Schwartz J, Arias IM (2005). "Rab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells". Proc. Natl. Acad. Sci. U.S.A. 102 (42): 15087–92. doi:10.1073/pnas.0503702102. PMC 1257697. PMID 16214890. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1257697.
External links