MYCBP
C-Myc-binding protein is a protein that in humans is encoded by the MYCBP gene.[1][2]
The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.[supplied by OMIM][2]
Interactions
MYCBP has been shown to interact with AKAP1,[3][4] C3orf15[3] and Myc.[1]
References
- ^ a b Taira T, Maeda J, Onishi T, Kitaura H, Yoshida S, Kato H, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H (Dec 1998). "AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC". Genes Cells 3 (8): 549–65. doi:10.1046/j.1365-2443.1998.00206.x. PMID 9797456.
- ^ a b "Entrez Gene: MYCBP c-myc binding protein". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26292.
- ^ a b Yukitake, Hiroshi; Furusawa Makoto, Taira Takahiro, Iguchi-Ariga Sanae M M, Ariga Hiroyoshi (Nov. 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J. Biol. Chem. (United States) 277 (47): 45480–92. doi:10.1074/jbc.M206201200. ISSN 0021-9258. PMID 12223483.
- ^ Furusawa, M; Ohnishi T, Taira T, Iguchi-Ariga S M, Ariga H (Sep. 2001). "AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase". J. Biol. Chem. (United States) 276 (39): 36647–51. doi:10.1074/jbc.M103885200. ISSN 0021-9258. PMID 11483602.
Further reading
- Furusawa M, Ohnishi T, Taira T, et al. (2001). "AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase.". J. Biol. Chem. 276 (39): 36647–51. doi:10.1074/jbc.M103885200. PMID 11483602.
- Yukitake H, Furusawa M, Taira T, et al. (2002). "AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.". Biochim. Biophys. Acta 1577 (1): 126–32. PMID 12151104.
- Yukitake H, Furusawa M, Taira T, et al. (2003). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase.". J. Biol. Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
- Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (2003). "AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.". J. Biol. Chem. 277 (52): 50885–92. doi:10.1074/jbc.M206387200. PMID 12414807.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Tomsig JL, Snyder SL, Creutz CE (2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.". J. Biol. Chem. 278 (12): 10048–54. doi:10.1074/jbc.M212632200. PMID 12522145.
- Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Ishizaki R, Shin HW, Iguchi-Ariga SM, et al. (2006). "AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.". Genes Cells 11 (8): 949–59. doi:10.1111/j.1365-2443.2006.00991.x. PMID 16866877.
- Sedoris KC, Thomas SD, Miller DM (2007). "c-myc promoter binding protein regulates the cellular response to an altered glucose concentration.". Biochemistry 46 (29): 8659–68. doi:10.1021/bi7003558. PMID 17595061.