MK-9470

MK-9470
IUPAC name

N-((2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Identifiers
CAS number 945850-36-2
PubChem 11167344
Jmol-3D images Image 1
Properties
Molecular formula C29H33N3O3
Molar mass 471.59 g/mol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

MK-9470 is a synthetic compound, which binds to the CB1 cannabinoid receptor and functions as an inverse agonist.[1]

References

  1. ^ Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ (2007). "[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9800–5. Bibcode 2007PNAS..104.9800B. doi:10.1073/pnas.0703472104. PMC 1877985. PMID 17535893. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1877985.