MED25
Mediator of RNA polymerase II transcription subunit 25 is an enzyme that in humans is encoded by the MED25 gene.[1][2][3]
Interactions
MED25 has been shown to interact with MED4.[4]
References
- ^ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139146.
- ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072.
- ^ "Entrez Gene: MED25 mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81857.
- ^ Tomomori-Sato, Chieri; Sato Shigeo, Parmely Tari J, Banks Charles A S, Sorokina Irina, Florens Laurence, Zybailov Boris, Washburn Michael P, Brower Christopher S, Conaway Ronald C, Conaway Joan Weliky (Feb. 2004). "A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2". J. Biol. Chem. (United States) 279 (7): 5846–51. doi:10.1074/jbc.M312523200. ISSN 0021-9258. PMID 14638676.
Further reading
- Näär AM, Beaurang PA, Zhou S, et al. (1999). "Composite co-activator ARC mediates chromatin-directed transcriptional activation.". Nature 398 (6730): 828–32. doi:10.1038/19789. PMID 10235267.
- Wang C, McCarty IM, Balazs L, et al. (2002). "A prostate-derived cDNA that is mapped to human chromosome 19 encodes a novel protein.". Biochem. Biophys. Res. Commun. 296 (2): 281–7. doi:10.1016/S0006-291X(02)00872-0. PMID 12163014.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Sato S, Tomomori-Sato C, Banks CA, et al. (2004). "A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.". J. Biol. Chem. 278 (50): 49671–4. doi:10.1074/jbc.C300444200. PMID 14576168.
- Tomomori-Sato C, Sato S, Parmely TJ, et al. (2004). "A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.". J. Biol. Chem. 279 (7): 5846–51. doi:10.1074/jbc.M312523200. PMID 14638676.
- Mittler G, Stühler T, Santolin L, et al. (2004). "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.". EMBO J. 22 (24): 6494–504. doi:10.1093/emboj/cdg619. PMC 291814. PMID 14657022. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=291814.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Yang F, DeBeaumont R, Zhou S, Näär AM (2004). "The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2339–44. doi:10.1073/pnas.0308676100. PMC 356952. PMID 14983011. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356952.
- Sato S, Tomomori-Sato C, Parmely TJ, et al. (2004). "A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.". Mol. Cell 14 (5): 685–91. doi:10.1016/j.molcel.2004.05.006. PMID 15175163.
- Zhang X, Krutchinsky A, Fukuda A, et al. (2005). "MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.". Mol. Cell 19 (1): 89–100. doi:10.1016/j.molcel.2005.05.015. PMID 15989967.
- Lee HK, Park UH, Kim EJ, Um SJ (2007). "MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.". EMBO J. 26 (15): 3545–57. doi:10.1038/sj.emboj.7601797. PMC 1949011. PMID 17641689. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1949011.
External links