Lothbury is a street in the City of London. It runs east-west, between Gresham Street to the west and Throgmorton Street to the east. The area was populated with coppersmiths in the Middle Ages before later becoming home to a number of merchants and bankers. The Bank of England is on the southern side of Lothbury, and some of Sir John Soane’s work dating from 1788 can be seen today. Opposite the Bank is the church of St Margaret Lothbury by Wren.
41 Lothbury is a particularly noteworthy office building, with its interior columns, marble walls and floor, and was for many years the head office of National Westminster Bank. At the beginning of the 20th century, the Great Northern & City Railway planned an underground railway station at Lothbury, but this was abandoned because of financial constraints. Today the nearest London Underground station is Bank a short way to the south.
Lothbury was the London home of the Kilgrew family of Cornwall in the late 16th / early 17th centuries. The Kiligrews were related to the Greshams who had a home nearby. These facts may explain the origin of these street names. Anne Kiligrew was one of seven talented daughters. Anne married Henry Neville a scholar, diplomat, and possible author of the Shakespeare canon according to Breda James in her book "The truth will out".