Linopirdine

Linopirdine

Systematic (IUPAC) name
1-phenyl-3,3-bis(pyridin-4-ylmethyl)-1,3-dihydro-2H-indol-2-one
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	105431-72-9^N
ATC code	N06BX09
PubChem	CID 3932
ChemSpider	3795^Y
UNII	I5TB3NZ94T^Y
KEGG	D04741^Y
ChEMBL	CHEMBL319111^Y
Chemical data
Formula	C₂₆H₂₁N₃O
Mol. mass	391.465 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2^Y Key:YEJCDKJIEMIWRQ-UHFFFAOYSA-N^Y
N(what is this?) (verify)

Linopirdine is a psychostimulant/nootropic, which has neuroprotective effects. It acts as a potassium channel blocker, and releases acetylcholine, which is probably responsible for its nootropic action.

References

Channel blocker: potassium channel blockers

Antiarrhythmic III/delayed rectifier	benzofuran (Amiodarone) • quaternary ammonium (Bretylium) • naphthalene (Bunaftine) • phenethylamine (Dofetilide) • sulfonamide (Ibutilide) • pyrimidinone (Nifekalant) • ethanolamine (Sotalol) • cyclopropane (Tedisamil) • E-4031

Other/ungrouped/unknown	aminopyridines (3,4-Diaminopyridine, 4-Aminopyridine) • indole (Linopirdine, Paxilline) • quaternary ammonium (Tetraethylammonium) • peptide (Maurotoxin, Charybdotoxin)

Centrally acting sympathomimetics

Xanthine derivatives

Racetams	Aniracetam • Nefiracetam • Noopept • Oxiracetam • Phenylpiracetam • Piracetam • Pramiracetam

Ampakines	CX-516 • CX-546 • CX-614 • CX-691 • CX-717 • IDRA-21 • LY-404,187 • LY-503,430 • PEPA • S-18986 • Sunifiram • Unifiram