Laninamivir

Laninamivir
Systematic (IUPAC) name
(4S,5R,6R)-5-acetamido-4-carbamimidamido-6-[(1R,2R)-3-hydroxy-2-methoxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid
Clinical data
Pregnancy cat.  ?
Legal status  ?
Routes Inhalation
Identifiers
CAS number 203120-17-6 N
ATC code None
PubChem CID 502272
ChemSpider 439182 Y
UNII B408IW3GL5 Y
ChEMBL CHEMBL466246 Y
Chemical data
Formula C13H22N4O7 
Mol. mass 346.33638 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Laninamivir (CS-8958) is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B.[1] It is currently in Phase III clinical trials.[2]

References

  1. ^ Yamashita M, Tomozawa T, Kakuta M, Tokumitsu A, Nasu H, Kubo S (January 2009). "CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity". Antimicrobial Agents and Chemotherapy 53 (1): 186–92. doi:10.1128/AAC.00333-08. PMC 2612152. PMID 18955520. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2612152. 
  2. ^ Hayden F (January 2009). "Developing new antiviral agents for influenza treatment: what does the future hold?". Clinical Infectious Diseases. 48 Suppl 1 (S1): S3–13. doi:10.1086/591851. PMID 19067613.