Lactucin

Lactucin
IUPAC name

(3aR,4R,9aS,9bR)-4-Hydroxy-9-(hydroxymethyl)-6-methyl-3-methylene-4,5,9a,9b-tetrahydro-3aH-azuleno[5,4-d]furan-2,7-dione
Identifiers
CAS number 1891-29-8
PubChem 821383
Jmol-3D images Image 1
Properties
Molecular formula C15H16O5
Molar mass 276.28 g/mol
Appearance White crystalline solid
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones. It is found in some varieties of lettuce and is an ingredient of lactucarium. It has been shown to have analgesic and sedative properties.[1]

It acts as adenosine receptor agonist.

See also

References

  1. ^ Wesołowska A, Nikiforuk A, Michalska K, Kisiel W, Chojnacka-Wójcik E (2006). "Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice". J Ethnopharmacol 107 (2): 254–8. doi:10.1016/j.jep.2006.03.003. PMID 16621374.