Wound

Wound
Classification and external resources

Wounded man
ICD-10 T14.0-T14.1
ICD-9 872-893
MeSH D014947

A wound is a type of injury in which skin is torn, cut or punctured (an open wound), or where blunt force trauma causes a contusion (a closed wound). In pathology, it specifically refers to a sharp injury which damages the dermis of the skin.

Contents

Classification

Open

Open wounds can be classified according to the object that caused the wound. The types of open wound are:

Closed

Closed wounds have fewer categories, but are just as dangerous as open wounds. The types of closed wounds are:

Pathophysiology

To heal a wound, the body undertakes a series of actions collectively known as the wound healing process.

Management

The treatment depends on the type, cause, and depth of the wound as well as whether other structure beyond the skin are involved. Treatment of recent lacerations involves examination, cleaning, and closing the wound. If the laceration occurred some time ago it may be allowed to heal by secondary intention due to the high rate of infection with immediate closure. Minor wounds like bruises will heal on their own with skin discoloration usually disappears in 1–2 weeks. Abrasions which are wounds with intact skin usually require no active treatment except keeping the area clean with soap and water. Puncture wounds may be prone to infection depending on the depth of penetration. The entry of puncture wound is left open to allow for bacteria or debris to be removed from inside.

Cleaning

For simple lacerations cleaning can be accomplished using a number of different solutions including tap water, sterile saline solution, or antiseptic solution. Infection rates may be lower with the use of tap water in regions where water quality is high.[1] Evidence for the effectiveness of any cleaning of simple wound however is limited.[1]

Closure

If a person presents within 6 hours of a laceration they are typically closed immediately. After this point in time however there is a theoretical concern of increased risks of infection if closed immediately.[2] Thus some may delay closure while other may close immediately up till 24 hours.[2] A single study has found that using clean non sterile gloves is equivalent to using sterile gloves during wound closure.[3][4]

If closure of a wound is decided upon a number of techniques can be used. These include bandages, a cyanoacrylate glue, staples, and sutures. Absorbable sutures have the benefit over non absorbable sutures of not requiring removal. They are often preferred in children.[5] Buffering the pH of lidocaine makes the freezing less painful.[6]

Dressings

The effectiveness of dressings and creams containing silver to prevent infection or improve healing is not currently supported by evidence.[7]

Antibiotics

Most clean open wounds do not require any antibiotics unless the wound is contaminated or the bacterial cultures are positive. Excess use of antibiotics only leads to resistance and side effects. All open wounds should be cleaned at least twice a day with warm water and soap. Once the wound is cleaned, it should be covered with moist gauze. This should be followed by application of dry gauze and then the wound covered with a bandage. The purpose of a wet to dry dressing allows the bandage to adhere to dead tissue performing a mechanical debridement when removed.This allows new healthy skin to grow and prevents debris from collecting. When the wound is clean, it may be closed with a skin graft. No wound is ever closed if it is suspected to be infected.[8]

Complications

Bacterial infection of wound can impede the healing process and lead to life threatening complications. Scientists at Sheffield University have identified a way of using light to rapidly detect the presence of bacteria. They are developing a portable kit in which specially designed molecules emit a light signal when bound to bacteria. Current laboratory-based detection of bacteria can take hours or even days.[9]

Workup

Individuals who have wounds that are not healing should be investigated to find the causes. Many microbiological agents can be responsible for this. The basic workup includes evaluating the wound, its extent and severity. Cultures are usually obtained both from the wound site and blood. X rays are obtained and a tetanus shot may be administered if there is any doubt about prior vaccination [10]

Chronic

Non-healing wounds of the diabetic foot are considered one of the most significant complications of diabetes, representing a major worldwide medical, social, and economic burden that greatly affects patient quality of life. Almost 24 million Americans—one in every 12—are diabetic and the disease is causing widespread disability and death at an epidemic pace, according to the Centers for Disease Control and Prevention. Of those with diabetes, 6.5 million are estimated to suffer with chronic or non-healing wounds. Associated with inadequate circulation, poorly functioning veins, and immobility, non-healing wounds occur most frequently in the elderly and in people with diabetes—populations that are sharply rising as the nation ages and chronic diseases increase.

Although diabetes can ravage the body in many ways, non-healing ulcers on the feet and lower legs are common outward manifestations of the disease. Also, diabetics often suffer from nerve damage in their feet and legs, allowing small wounds or irritations to develop without awareness. Given the abnormalities of the microvasculature and other side effects of diabetes, these wounds take a long time to heal and require a specialized treatment approach for proper healing.

As many as 25% of diabetic patients will eventually develop foot ulcers, and recurrence within five years is 70%. If not aggressively treated, these wounds can lead to amputations. It is estimated that every 30 seconds a lower limb is amputated somewhere in the world because of a diabetic wound. Amputation often triggers a downward spiral of declining quality of life, frequently leading to disability and death. In fact, only about one third of diabetic amputees will live more than five years, a survival rate equivalent to that of many cancers.

Many of these lower extremity amputations can be prevented through an interdisciplinary approach to treatment involving a variety of advanced therapies and techniques, such as debridement, hyperbaric oxygen treatment therapy, dressing selection, special shoes, and patient education. When wounds persist, a specialized approach is required for healing.[11]

History

From the Classical Period to the Medieval Period, the body and the soul were believed to be intimately connected, based on several theories put forth by the philosopher Plato. Wounds on the body were believed to correlate with wounds to the soul and vice versa; wounds were seen as an outward sign of an inward illness. Thus, a man who was wounded physically in a serious way was said to be hindered not only physically but spiritually as well. If the soul was wounded, that wound may also eventually become physically manifest, revealing the true state of the soul.[12] Wounds were also seen as writing on the "tablet" of the body. Wounds acquired in war, for example, told the story of a soldier in a form which all could see and understand, and the wounds of a martyr told the story of their faith.[12]

See also

References

  1. ^ a b Fernandez R, Griffiths R (2008). Fernandez, Ritin. ed. "Water for wound cleansing". Cochrane Database Syst Rev (1): CD003861. doi:10.1002/14651858.CD003861.pub2. PMID 18254034. 
  2. ^ a b Eliya, MC; Banda, GW (2011 Sep 7). Eliya, Martha C. ed. "Primary closure versus delayed closure for non bite traumatic wounds within 24 hours post injury". Cochrane database of systematic reviews (Online) 9: CD008574. doi:10.1002/14651858.CD008574.pub2. PMID 21901725. 
  3. ^ Perelman, VS; Francis, GJ, Rutledge, T, Foote, J, Martino, F, Dranitsaris, G (2004 Mar). "Sterile versus nonsterile gloves for repair of uncomplicated lacerations in the emergency department: a randomized controlled trial.". Annals of emergency medicine 43 (3): 362–70. PMID 14985664. 
  4. ^ van den Broek, PJ (2011). "[Sterile gloves are necessary in minor surgery].". Nederlands tijdschrift voor geneeskunde 155 (18): A3341. PMID 21466736. 
  5. ^ "BestBets: Absorbable sutures in pediatric lacerations". http://www.bestbets.org/bets/bet.php?id=874. 
  6. ^ Cepeda MS, Tzortzopoulou A, Thackrey M, Hudcova J, Arora Gandhi P, Schumann R (2010). Tzortzopoulou, Aikaterini. ed. "Adjusting the pH of lidocaine for reducing pain on injection". Cochrane Database Syst Rev 12 (12): CD006581. doi:10.1002/14651858.CD006581.pub2. PMID 21154371. 
  7. ^ D'Amico G, Pagliaro L, Pietrosi G, Tarantino I (2010). d'Amico, Gennaro. ed. "Emergency sclerotherapy versus vasoactive drugs for bleeding oesophageal varices in cirrhotic patients". Cochrane Database Syst Rev 3 (3): CD002233. doi:10.1002/14651858.CD002233.pub2. PMID 20238318. 
  8. ^ Wound Infection Signs And Preventive Measures. Retrieved on 2010-01-27
  9. ^ "Light to detect wound infection" (web). UK scientists have identified a way of using light to rapidly detect the presence of bacteria. bodat. BBC News. 11 March 2007. http://news.bbc.co.uk/1/hi/health/6427787.stm. Retrieved 2008-03-17. 
  10. ^ Work Up eMedicine General Surgery. Retrieved on 2010-01-27
  11. ^ "The Clinical Case for Use of Hyperbaric Oxygen Therapy in the Treatment of Diabetic Wounds," Diversified Clinical Services, copyright 2009
  12. ^ a b Reichardt, Paul F. (1984). "Gawain and the image of the wound". PMLA 99 (2): 154–161. doi:10.2307/462158. JSTOR 462158. 

External links