Methylarginine

Methylarginine
IUPAC name

(2S)-2-Amino-5-[(N′-methylcarbamimidoyl)amino]pentanoic acid
Other names

Targinina; Targininum; Targinine; omega-N-Methylarginine; L-Monomethylarginine; N-Methyl-L-arginine; N-Monomethyl-L-arginine; NG-monomethyl-L-arginine
Identifiers
Abbreviations L-NMMA
CAS number 17035-90-4 Y
PubChem 132862
ChEMBL CHEMBL256147 N
Jmol-3D images Image 1
Properties
Molecular formula C7H16N4O2
Molar mass 188.23 g/mol
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

N-Methylarginine is an inhibitor of nitric oxide synthase.[1] Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.

See also

References

  1. ^ Toutouzas, K.; Riga, M.; Stefanadi, E.; Stefanadis, C. (2008). "Asymmetric dimethylarginine (ADMA) and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance". Hormone and Metabolic Research 40 (9): 655–659. doi:10.1055/s-0028-1083814. PMID 18792879.