KRR1

KRR1, small subunit (SSU) processome component, homolog (yeast)

Identifiers

KRR1; HRB2; RIP-1

External IDs

OMIM: 612817 MGI: 1289274 HomoloGene: 5114 GeneCards: KRR1 Gene

Gene Ontology
Molecular function	• RNA binding
Cellular component	• nucleus • nucleolus • ribonucleoprotein complex
Biological process	• rRNA processing
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12:
75.89 – 75.91 Mb

Chr 10:
111.41 – 111.43 Mb

PubMed search

[1]

[2]

KRR1 small subunit processome component homolog is a protein that in humans is encoded by the KRR1 gene.^[1]^[2]^[3]^[4]^[5]

References

^ Epplen C, Epplen JT (Feb 1994). "Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes". Hum Genet 93 (1): 35–41. doi:10.1007/BF00218910. PMID 7505766.
^ Sasaki T, Toh-E A, Kikuchi Y (Oct 2000). "Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus". Mol Cell Biol 20 (21): 7971–9. doi:10.1128/MCB.20.21.7971-7979.2000. PMC 86407. PMID 11027267. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=86407.
^ Chan HY, Brogna S, O'Kane CJ (May 2001). "Dribble, the Drosophila KRR1p Homologue, Is Involved in rRNA Processing". Mol Biol Cell 12 (5): 1409–19. PMC 34593. PMID 11359931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=34593.
^ Gromadka R, Kaniak A, Slonimski PP, Rytka J (Aug 1996). "A novel cross-phylum family of proteins comprises a KRR1 (YCL059c) gene which is essential for viability of Saccharomyces cerevisiae cells". Gene 171 (1): 27–32. doi:10.1016/0378-1119(96)00024-8. PMID 8675026.
^ "Entrez Gene: KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11103.

Muthumani K, Choo AY, Premkumar A, et al. (2006). "Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism". Cell Death Differ. 12 Suppl 1: 962–70. doi:10.1038/sj.cdd.4401583. PMID 15832179.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=133617.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Micheau O, Tschopp J (2003). "Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes". Cell 114 (2): 181–90. doi:10.1016/S0092-8674(03)00521-X. PMID 12887920.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Bernstein KA, Gallagher JE, Mitchell BM, et al. (2005). "The Small-Subunit Processome Is a Ribosome Assembly Intermediate". Eukaryotic Cell 3 (6): 1619–26. doi:10.1128/EC.3.6.1619-1626.2004. PMC 539036. PMID 15590835. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=539036.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

KRR1

References

Further reading