| Coiled-coil domain containing 165 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbols | CCDC165; | ||||||
| External IDs | MGI: 1915867 HomoloGene: 41017 GeneCards: CCDC165 Gene | ||||||
|
|||||||
| RNA expression pattern | |||||||
| More reference expression data | |||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez | 23255 | 68617 | |||||
| Ensembl | ENSG00000168502 | ENSMUSG00000052105 | |||||
| UniProt | Q9Y4B5 | Q3UHU5 | |||||
| RefSeq (mRNA) | NM_015210 | NM_172963 | |||||
| RefSeq (protein) | NP_056025 | NP_766551 | |||||
| Location (UCSC) | Chr 18: 8.71 – 8.83 Mb |
Chr 17: 66.69 – 66.8 Mb |
|||||
| PubMed search | [1] | [2] | |||||
KIAA0802 also known as hypothetical protein LOC23255 is a protein that is encoded by the KIAA0802 gene.[1][2]
In humans, the gene coding sequence is 151,349 base pairs long, with an mRNA of 6092 base pairs, and a protein sequence of 1586 amino acids. The KIAA0802 gene is conserved in chimpanzee, dog, cow, mouse, rat, and chicken.
Contents |
Orthlogs have been identified in Eukaryotes[3][4][5][6].
| Organism | Protein Accession Number | Gene Accession Number | % Identity |
|---|---|---|---|
| Human | NP_056025 | NM_015210 | 100% |
| Chimpanzee | XP_001140422 | XM_001140422 | 96% |
| Sumatran Orangutan | XP_002828090 | XM_002828043.1 | 96% |
| Common Marmoset | XP_002757107 | XM_002757061.1 | 95% |
| Horse | XP_001489003 | XM_001488953.2 | 85% |
| Panda | XP_002917629 | XM_002917583.1 | 84% |
| Gray wolf | XP_547667 | XM_547667.2 | 83% |
| Brown rat | XP_237548 | XM_237548.5 | 82% |
| House mouse | NP_766551 | NM_172963.4 | 80% |
| Cattle | XP_581047 | XM_002697799.1 | 73% |
| Chicken | XP_423729 | XM_423729.2 | 70% |
| Western clawed frog | XP_002942331 | XM_002942285.1 | 39% |
| Zebrafish | XP_001338362 | XM_001338326.3 | 39% |
| Lancelet | XP_002588389 | XM_002588343.1 | 38% |
C20orf117 gene was identified as a paralog of KIAA0802[4].
In humans the expression of the KIAA0802 gene is increased in bones, the pituitary gland, ears, and eyes[4][3] . Moderate expression is found in other regions of the body including the esophagus, brain, and the lymph[3] .
Several amino acids are present in high concentrations in KIAA0802 compared to average human proteins. These higher than average concentrations have been identified for aspartic acid, glycine, glutamic acid, histidine, lysine, leucine, proline, arginine, and serine[7].
Protein complex co-immunoprecipitation (Co-IP) experiments revealed interacting proteins such as cell death regulators, ATP-binding cassette (ABC) transporters and protein kinase A binding proteins[8].
The 540 interacting proteins include ABCF1, ACTB, ACTL6A, BCLAF1, BCLAF1, CHEK1, and MAGEE2[8].
|
|||||